DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phae2 and PRSS36

DIOPT Version :9

Sequence 1:	NP_001285871.1	Gene:	Phae2 / 34638	FlyBaseID:	FBgn0263235	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_775773.2	Gene:	PRSS36 / 146547	HGNCID:	26906	Length:	855	Species:	Homo sapiens

Alignment Length:	286	Identity:	77/286 - (26%)
Similarity:	123/286 - (43%)	Gaps:	33/286 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RHLATILLLAVC-----VSQGSGLA--------LD----QPEGRVVGGKAAAANSAPYIVSMQYG 52
            |||...|::.|.     ..|.|.|:        ||    :|..|:|||..|...:.|:.||:.:|
Human     3 RHLLLPLVMLVISPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHG 67

  Fly    53 GTHYCAANIINSNWLVTAAHCLANRNQVLGS---TLVAGSIAVAGTASTTQKRQITHYVINDLYT 114
            |.|.|..::|..:|:::||||......:..:   :::.|..:..|.......|.:...|:...|:
Human    68 GGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYS 132

  Fly   115 GGTVPYDIGLIYTPTAFTWTAAVAPVKLPSSGVRPTGKADLF--GWGSTSKTNSPSYPKTLQEAK 177
            ...:..|:.|:...:..:...||.||.||.:..|.......:  |||...:.:....|..|||.:
Human   133 QVELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVE 197

  Fly   178 NIPIISLDSCAAALGSKGQ-----DVHTTNLCTGPLTGGTSFCTSDSGGPLV--QGN--VLIGIV 233
             :.::...:|.......|.     .:....||.|...|....|..|||||||  :|.  ...||.
Human   198 -LRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGIT 261

  Fly   234 SWGKLPCGQPNSPSVYVQVSSFITWI 259
            |:| ..||:.|.|.|:..|:::..||
Human   262 SFG-FGCGRRNRPGVFTAVATYEAWI 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_001285871.1	Tryp_SPc	31..259	CDD:214473	64/241 (27%)
Phae2	NP_001285871.1	Tryp_SPc	32..262	CDD:238113	65/242 (27%)
PRSS36	NP_775773.2	Tryp_SPc	46..286	CDD:214473	64/241 (27%)
		Tryp_SPc	47..289	CDD:238113	65/242 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..316
		Tryp_SPc	330..538	CDD:304450
		Tryp_SPc	601..783	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010