Protein Alignment Phae2 and KLK11

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 84/283 - (29%)
• Similarity: 119/283 - (42%)
• Gaps: 43/283 - (15%)

  Fly    10 ILLLAVCVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCL 74
            ::|||:......|      |.|::.|.....:|.|:..::.......|.|.:|...||:||||||
Human    38 LILLALATGLVGG------ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCL 96

  Fly    75 ANRNQVLGSTLVAGSIAVAGTASTTQKRQITHYVINDLYT-------------------GGTVP- 119
            .....:...|.|:..::.:....:...|.|.|...::|..                   ..::|
Human    97 KPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPN 161

  Fly   120 ----YDIGLI--YTPTAFTWTAAVAPVKLPSSGVRPTGKADLFGWGSTSKTNSPS--YPKTLQEA 176
                .||.|:  .:|.:.||  ||.|:.|.|..|.......:.||||||   ||.  .|.||:.|
Human   162 KDHRNDIMLVKMASPVSITW--AVRPLTLSSRCVTAGTSCLISGWGSTS---SPQLRLPHTLRCA 221

  Fly   177 KNIPIISLDSCAAALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGGPLVQGNVLIGIVSWGKLPCG 241
             ||.||....|..|...   ::..|.:|.....||...|..|||||||....|.||:|||:.||.
Human   222 -NITIIEHQKCENAYPG---NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCA 282

  Fly   242 QPNSPSVYVQVSSFITWIAANQK 264
            ....|.||.:|..::.||....|
Human   283 ITRKPGVYTKVCKYVDWIQETMK 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	77/257 (30%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	76/255 (30%)