DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Phae2 and tmprss2.12

DIOPT Version :10

Sequence 1:NP_609551.2 Gene:Phae2 / 34638 FlyBaseID:FBgn0263235 Length:265 Species:Drosophila melanogaster
Sequence 2:XP_031752400.1 Gene:tmprss2.12 / 100497514 XenbaseID:XB-GENE-22065925 Length:497 Species:Xenopus tropicalis


Alignment Length:244 Identity:76/244 - (31%)
Similarity:120/244 - (49%) Gaps:25/244 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 EGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLANRNQVLGST-------LV 86
            |.|:|||.:|:....|:.|::||..|:.|..::|.:||:||||||      |.|.|       ..
 Frog   258 ESRIVGGSSASIGDWPWQVNLQYDDTNLCGGSVIAANWIVTAAHC------VQGDTSSPSLWKAF 316

  Fly    87 AGSIAVAGTASTTQKRQITHYVINDLYTGGTVPYDIGLIYTPTAFTWTAAVAPVKLPSSGVR-PT 150
            .|.|.:.....:: ...:...:::..|:..|...||.|:...|:..:::...||.||:.|:: ..
 Frog   317 IGKIKMPSYYDSS-AYSVDRIIVHPDYSSQTNSNDIALMKLKTSIAFSSISRPVCLPNYGMQWEE 380

  Fly   151 GK-ADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGSKGQDVHTTNLCTGPLTGGTSF 214
            |: ..:.|||:||:..|.|  ..|:.|. :|:||..:|...:...|. :.::.:|.|...||...
 Frog   381 GQPCYISGWGTTSQKGSIS--SVLKYAM-VPLISPTTCNQTIMYNGA-ITSSMICAGYPKGGVDS 441

  Fly   215 CTSDSGGPLVQGN----VLIGIVSWGKLPCGQPNSPSVYVQVSSFITWI 259
            |..|||||||...    .|:|..|||. .|.....|.||..::.|:.||
 Frog   442 CQGDSGGPLVTKTNSLWWLVGDTSWGD-GCANVYRPGVYGNMTVFLQWI 489

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Phae2NP_609551.2 Tryp_SPc 32..262 CDD:238113 74/241 (31%)
tmprss2.12XP_031752400.1 LDLa 127..155 CDD:238060
SRCR_2 160..255 CDD:464747
Tryp_SPc 261..489 CDD:238113 72/239 (30%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.