Protein Alignment Phae1 and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 84/254 - (33%)
• Similarity: 122/254 - (48%)
• Gaps: 19/254 - (7%)

  Fly    25 SGVAIGAPEGRVVGGSPAAVNSAPYAVSMQYGGTHYCAASILNANWLVTAAHC--LTNSNQVLGS 87
            |...:.|..||:|||:.|:.:..|:.||:.:|.||.|..::::|.|::|||||  :|....:.|.
Human   315 SHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGW 379

  Fly    88 TLVAGSIAVDGTASTTQTRSITYFVINDLYTGGTVPYDIGMIYTPTAFVWSAAVAPVTLPSSGVV 152
            .:.||:   .......:..||...:||..||.....|||.::........||.:.|..||..|
Human   380 KVYAGT---SNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHG-- 439

  Fly   153 PTGTAN----LYGWGSTSTTNTASYPSTLQVATNVPIISLSSCESALGTKGSDVHSTNLCTGPLT 213
            .|.:.|    :.|:|.|..|:..:.|...:|..|  :|....|...| ...|.:....:|.|.|.
Human   440 QTFSLNETCWITGFGKTRETDDKTSPFLREVQVN--LIDFKKCNDYL-VYDSYLTPRMMCAGDLR 501

  Fly   214 GGVSICTSDSGGPLV--QGN--VLIGIVSWGKLPCGQANSPSVYVQVSSFISWISANQQ 268
            ||...|..|||||||  |.|  .|.|:.||| ..|||.|.|.||.:|:..:.||.:..:
Human   502 GGRDSCQGDSGGPLVCEQNNRWYLAGVTSWG-TGCGQRNKPGVYTKVTEVLPWIYSKME 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	80/239 (33%)
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747	1/5 (20%)
		Tryp_SPc	325..554	CDD:214473	79/237 (33%)