Protein Alignment Phae1 and PRSS22

DIOPT Version :10

• Sequence 1: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 85/251 - (33%)
• Similarity: 128/251 - (50%)
• Gaps: 20/251 - (7%)

  Fly    28 AIGAPE--GRVVGGSPAAVNSAPYAVSMQYGGTHYCAASILNANWLVTAAHCL-TNSNQVLGSTL 89
            |.|.|:  .|||||..:..:..|:.||:|..|||:||.|:|.:.|::|||||. .|.|:....::
Human   148 ACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSV 212

  Fly    90 VAGSIAVDGTASTTQTRSITYFVINDLYT---GGTVPYDIGMIYTPTAFVWSAAVAPVTLPSSGV 151
            :.|:..:....|.:|...:.:...:.:|:   |...  ||.::....:..:|..|.|:.||.:.:
Human   213 LLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACA--DIALVRLERSIQFSERVLPICLPDASI 275

  Fly   152 -VPTGT-ANLYGWGSTSTTNTASYPSTLQVATNVPIISLSSCESALGTKGS---DVHSTNLCTGP 211
             :|..| ..:.||||........:|.||| ...||||....| |.|..:|:   .:....||.|.
Human   276 HLPPNTHCWISGWGSIQDGVPLPHPQTLQ-KLKVPIIDSEVC-SHLYWRGAGQGPITEDMLCAGY 338

  Fly   212 LTGGVSICTSDSGGPL---VQGN-VLIGIVSWGKLPCGQANSPSVYVQVSSFISWI 263
            |.|....|..||||||   |.|. :|.||:|||: .|.:.|.|.||:.:|:..||:
Human   339 LEGERDACLGDSGGPLMCQVDGAWLLAGIISWGE-GCAERNRPGVYISLSAHRSWV 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	81/241 (34%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	81/241 (34%)