Protein Alignment Phae1 and PRSS1

DIOPT Version :10

• Sequence 1: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 85/253 - (33%)
• Similarity: 129/253 - (50%)
• Gaps: 21/253 - (8%)

  Fly    15 LLLLLGICRISGVAIGAP---EGRVVGGSPAAVNSAPYAVSMQYGGTHYCAASILNANWLVTAAH 76
            ||:|..:    ..|:.||   :.::|||.....||.||.||:. .|.|:|..|::|..|:|:|.|
Human     4 LLILTFV----AAALAAPFDDDDKIVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGH 63

  Fly    77 CLTNSNQVLGSTLVAGSIAVDGTASTTQTRSITYFVINDLYTGGTVPYDIGMIYTPTAFVWSAAV 141
            |..:..||.     .|...::......|..:....:.:..|...|:..||.:|...:..|.:|.|
Human    64 CYKSRIQVR-----LGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARV 123

  Fly   142 APVTLPSSGVVPTGTANLY-GWGSTSTTNTASYPSTLQVATNVPIISLSSCESALGTKGSDVHST 205
            :.::||::... |||..|. |||:|:::. |.||..|| ..:.|::|.:.||::...|   :.|.
Human   124 STISLPTAPPA-TGTKCLISGWGNTASSG-ADYPDELQ-CLDAPVLSQAKCEASYPGK---ITSN 182

  Fly   206 NLCTGPLTGGVSICTSDSGGPLVQGNVLIGIVSWGKLPCGQANSPSVYVQVSSFISWI 263
            ..|.|.|.||...|..|||||:|....|.|:||||. .|.|.|.|.||.:|.:::.||
Human   183 MFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWI 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	79/229 (34%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	77/228 (34%)