Protein Alignment Phae1 and PRSS57

DIOPT Version :10

• Sequence 1: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_999875.2
• Gene: PRSS57 / 400668
• HGNCID: 31397
• Length: 283
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 79/275 - (28%)
• Similarity: 121/275 - (44%)
• Gaps: 41/275 - (14%)

  Fly     5 GQQTKSLASGLLLLLGICRISGVAIGAPEG----RVVGGSPAAVNSAPYAVSMQYGGTHYCAASI 65
            |:...::|:.|:|          .:..|.|    :::||.....:|.||..|:::||.|:|...:
Human     9 GRPLLTVATALML----------PVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFL 63

  Fly    66 LNANWLVTAAHCLTNSNQVLGSTLVAGSIAVDGTASTTQTRSITYFVINDLYTGGTVPYDIGMIY 130
            |.|.|:|:||||.::.:...| .:|.|:..:.....|.|...|.....:..|...|...||.::.
Human    64 LRARWVVSAAHCFSHRDLRTG-LVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLR 127

  Fly   131 TPTAFVWSAAVAPVTLPSSGVVP--TGT-ANLYGWGSTSTTNTASYPSTLQVATNVPIISLSSCE 192
            ...:.|...||..:..|.....|  .|| ..:.|||..|  :....|..|..| .|.::....|.
Human   128 LNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVS--DFEELPPGLMEA-KVRVLDPDVCN 189

  Fly   193 SA---------LGTKGSDVHSTNLCTGPLTGGVSICTSDSGGPLVQGNVLIGIVSWGKLPCGQAN 248
            |:         |.|:..|.|..           ..|::|||||||..|...|:||:..|.||...
Human   190 SSWKGHLTLTMLCTRSGDSHRR-----------GFCSADSGGPLVCRNRAHGLVSFSGLWCGDPK 243

  Fly   249 SPSVYVQVSSFISWI 263
            :|.||.|||:|::||
Human   244 TPDVYTQVSAFVAWI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	73/240 (30%)
PRSS57	NP_999875.2	Tryp_SPc	34..258	CDD:238113	71/238 (30%)