Protein Alignment Phae1 and KLKB1

DIOPT Version :10

• Sequence 1: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: XP_011530232.1
• Gene: KLKB1 / 3818
• HGNCID: 6371
• Length: 649
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 78/282 - (27%)
• Similarity: 120/282 - (42%)
• Gaps: 26/282 - (9%)

  Fly     2 LANGQQTKSLASGLLLLLGICRI--SGVAIGAPEGRVVGGSPAAVNSAPYAVSMQYGGT---HYC 61
            :|.|.|..|..|     |.:|..  :.|.......|:|||:.::....|:.||:|...|   |.|
Human   371 IAYGTQGSSGYS-----LRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLC 430

  Fly    62 AASILNANWLVTAAHCLTNSNQVLGSTLVAGSIAVDGTASTTQTRSITYFVINDLYTGGTVPYDI 126
            ..|::...|::|||||...........:.:|.:.:......|....|...:|:..|......:||
Human   431 GGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDI 495

  Fly   127 GMIYTPTAFVWSAAVAPVTLPSSGVVPTGTANLY--GWGSTSTTNTASYPSTLQVATNVPIISLS 189
            .:|.......::....|:.|||.|...|...|.:  |||.:.  ......:.|| ..|:|:::..
Human   496 ALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSK--EKGEIQNILQ-KVNIPLVTNE 557

  Fly   190 SCESALGTKGSDVHSTN--LCTGPLTGGVSICTSDSGGPLVQGN----VLIGIVSWGKLPCGQAN 248
            .|:.    :..|...|.  :|.|...||...|..|||||||..:    .|:||.|||: .|.:..
Human   558 ECQK----RYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARRE 617

  Fly   249 SPSVYVQVSSFISWISANQQVS 270
            .|.||.:|:.::.||....|.|
Human   618 QPGVYTKVAEYMDWILEKTQSS 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	67/240 (28%)
KLKB1	XP_011530232.1	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	212..295	CDD:128519
		APPLE	303..386	CDD:128519	6/19 (32%)
		Tryp_SPc	402..632	CDD:238113	65/237 (27%)