Protein Alignment Phae1 and PRSS48

DIOPT Version :10

• Sequence 1: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 84/272 - (30%)
• Similarity: 120/272 - (44%)
• Gaps: 38/272 - (13%)

  Fly    15 LLLLLGICRISGVAIGAP--EGRVVGGSPAAVNSAPYAVSMQYGGTHYCAASILNANWLVTAAHC 77
            |||||||.     ..|.|  ..|||||..||....|:.||:.:.....|..|:::...::|||||
Human    10 LLLLLGIS-----VCGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHC 69

  Fly    78 LTNSNQVLGSTLVAGSIAVDGTASTTQTRSITYFVINDLYTGGTVPYDIGMIYTPTAFVWSAAVA 142
            :..:......|:..|||.| |.:.......::..||:..|...|.  |:.::...:...:::|:.
Human    70 IQPTWTTFSYTVWLGSITV-GDSRKRVKYYVSKIVIHPKYQDTTA--DVALLKLSSQVTFTSAIL 131

  Fly   143 PVTLPSSGVVPTGTANL--------YGWGSTSTTNTASYPSTLQVATNVPIISLSSCESALGTKG 199
            |:.|||.      |..|        .|||....::...|.|.||.| .||||...:||......|
Human   132 PICLPSV------TKQLAIPPFCWVTGWGKVKESSDRDYHSALQEA-EVPIIDRQACEQLYNPIG 189

  Fly   200 -------SDVHSTNLCTGPLTGGVSICTSDSGGPL---VQGN-VLIGIVSWGKLPCGQANSPSVY 253
                   ..:....:|.|........|..||||||   :.|. :..|:|||| |.||: :.|.||
Human   190 IFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWG-LECGK-SLPGVY 252

  Fly   254 VQVSSFISWISA 265
            ..|..:..||:|
Human   253 TNVIYYQKWINA 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	74/249 (30%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	74/249 (30%)