Protein Alignment Phae1 and KLK5

DIOPT Version :10

• Sequence 1: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 72/273 - (26%)
• Similarity: 112/273 - (41%)
• Gaps: 61/273 - (22%)

  Fly    29 IGAPEG----------RVVGGSPAAVNSAPYAVSMQYGGTH-YCAASILNANWLVTAAHCLTNSN 82
            :||..|          |::.||...:::.|:..::...... ||.|.:::..||:|||||.....
Human    50 LGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVF 114

  Fly    83 QV-LGSTLVAGSIAVDGTASTTQTRSITYFVINDLYTGG--------TVPY----------DIGM 128
            :| ||                       ::.::.:|..|        ::|:          |:.:
Human   115 RVRLG-----------------------HYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLML 156

  Fly   129 IYTPTAFVWSAAVAPVTLPSSGVVPTGTANLY-GWGSTSTTNTASYPSTLQVATNVPIISLSSCE 192
            |........:..|.|:.: ||.....||..|. |||:|.:.. ..:|..|| ..|:.::|...||
Human   157 IKLNRRIRPTKDVRPINV-SSHCPSAGTKCLVSGWGTTKSPQ-VHFPKVLQ-CLNISVLSQKRCE 218

  Fly   193 SALGTKGSDVHSTNLCTGPLTGGVSICTSDSGGPLVQGNVLIGIVSWGKLPCGQANSPSVYVQVS 257
            .|...:   :..|..|.|...|..| |..|||||:|....|.|:||||..||.:.|.|.||..:.
Human   219 DAYPRQ---IDDTMFCAGDKAGRDS-CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLC 279

  Fly   258 SFISWISANQQVS 270
            .|..||....|.:
Human   280 KFTKWIQETIQAN 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	67/250 (27%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/17 (24%)
		Tryp_SPc	66..285	CDD:214473	66/248 (27%)