DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phae1 and Klkb1

DIOPT Version :9

Sequence 1:	NP_001285870.1	Gene:	Phae1 / 34637	FlyBaseID:	FBgn0263234	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	80/265 - (30%)
Similarity:	117/265 - (44%)	Gaps:	21/265 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LGICRI--SGVAIGAPEGRVVGGSPAAVNSAPYAVSMQ---YGGTHYCAASILNANWLVTAAHCL 78
            |.:|::  |.........|:|||:.:::...|:.||:|   ....|.|..||:...|::|||||.
  Rat   372 LRLCKVVESSDCTTKINARIVGGTNSSLGEWPWQVSLQVKLVSQNHMCGGSIIGRQWILTAAHCF 436

  Fly    79 TNSNQVLGSTLVAGSIAVDGTASTTQTRSITYFVINDLYTGGTVPYDIGMIYTPTAFVWSAAVAP 143
            ..........:..|.:.:....:.|...||...:|:..|......|||.:|...|...::....|
  Rat   437 DGIPYPDVWRIYGGILNLSEITNKTPFSSIKELIIHQKYKMSEGSYDIALIKLQTPLNYTEFQKP 501

  Fly   144 VTLPSSGVVPTGTANLY--GWGSTSTTNTASYPSTLQVATNVPIISLSSCESALGTKGSDVHSTN 206
            :.|||.....|...|.:  |||.|.......  :.||.|| :|::....|:.    |..|...|.
  Rat   502 ICLPSKADTNTIYTNCWVTGWGYTKERGETQ--NILQKAT-IPLVPNEECQK----KYRDYVITK 559

  Fly   207 --LCTGPLTGGVSICTSDSGGPLV---QGN-VLIGIVSWGKLPCGQANSPSVYVQVSSFISWISA 265
              :|.|...||:..|..|||||||   .|. .|:||.|||: .|.:...|.||.:|:.:|.||..
  Rat   560 QMICAGYKEGGIDACKGDSGGPLVCKHSGRWQLVGITSWGE-GCARKEQPGVYTKVAEYIDWILE 623

  Fly   266 NQQVS 270
            ..|.|
  Rat   624 KIQSS 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_001285870.1	Tryp_SPc	35..263	CDD:214473	73/238 (31%)
Phae1	NP_001285870.1	Tryp_SPc	36..266	CDD:238113	74/240 (31%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519	1/2 (50%)
		Tryp_SPc	390..621	CDD:214473	73/238 (31%)
		Tryp_SPc	391..621	CDD:238113	72/237 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910