DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phae1 and PRSS55

DIOPT Version :9

Sequence 1:	NP_001285870.1	Gene:	Phae1 / 34637	FlyBaseID:	FBgn0263234	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_940866.2	Gene:	PRSS55 / 203074	HGNCID:	30824	Length:	352	Species:	Homo sapiens

Alignment Length:	255	Identity:	70/255 - (27%)
Similarity:	109/255 - (42%)	Gaps:	40/255 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RVVGGSPAAVNSAPYAVSMQYGGTHYCAASILNANWLVTAAHCLTNS-------NQVLGSTLVAG 92
            |:.||..|.|...|:.||:|.....:|..||||..|::||||||.:.       :.|||:.
Human    67 RITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTN---- 127

  Fly    93 SIAVDGTASTTQTRSITYFVINDLYTGGTVPYDIGMIYTPTAFVWSAAVAPVTLPSSGVVPTGTA 157
                |.|:.:.:.:.:...:::..:....:..||.::...:.........|:.||:.    .|.|
Human   128 ----DLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQ----PGPA 184

  Fly   158 N-----LYGWGSTSTTNTASYPSTLQVATNVPIISLSSCESALG--TKGSDVHSTNLCTGPLTGG 215
            .     :.|||.|:..:..|..:.|..|..| |:....|.....  ||..      ||.|.....
Human   185 TWRECWVAGWGQTNAADKNSVKTDLMKAPMV-IMDWEECSKMFPKLTKNM------LCAGYKNES 242

  Fly   216 VSICTSDSGGPLV------QGNVLIGIVSWGKLPCGQANSPSVYVQVSSFISWISANQQV 269
            ...|..|||||||      :....:||:|||| .||:.|:|.:|..:.::..||....|:
Human   243 YDACKGDSGGPLVCTPEPGEKWYQVGIISWGK-SCGEKNTPGIYTSLVNYNLWIEKVTQL 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_001285870.1	Tryp_SPc	35..263	CDD:214473	67/247 (27%)
Phae1	NP_001285870.1	Tryp_SPc	36..266	CDD:238113	68/249 (27%)
PRSS55	NP_940866.2	Tryp_SPc	67..295	CDD:214473	67/247 (27%)
		Tryp_SPc	68..298	CDD:238113	68/249 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	308..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910