DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phae1 and svh-1

DIOPT Version :9

Sequence 1:	NP_001285870.1	Gene:	Phae1 / 34637	FlyBaseID:	FBgn0263234	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	268	Identity:	79/268 - (29%)
Similarity:	119/268 - (44%)	Gaps:	40/268 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 CRISGVAIGAPE------GRVVGGSPAAVNSAPYAVSMQYGGT--HYCAASILNANWLVTAAHCL 78
            |.:..|.:.|.:      .|||||......:.|:..:::...|  |:|.||||:...|:|||||.
Worm   693 CGLRYVEVNARDAAKSRIARVVGGFETVPGAFPWTAALRNKATKAHHCGASILDKTHLITAAHCF 757

  Fly    79 TNSNQVLGSTLVAG---SIAVDGTASTTQTRSITYF-VINDLYTGGTVPYDIGMIYTP-TAFVWS 138
            ....:|....:|.|   :...||.......:.|.:: :..|:::     :||.::..| ....::
Worm   758 EEDERVSSYEVVVGDWDNNQTDGNEQIFYLQRIHFYPLYKDIFS-----HDIAILEIPYPGIEFN 817

  Fly   139 AAVAPVTLPSSGVV--PTGTANLYGWGSTSTTNTASYPSTLQVATNVPIISLSSCESALGTKGSD 201
            ....|:.|||...|  |.....:.||||..    ..|...||.|. :|||:...|     ...|.
Worm   818 EYAQPICLPSKDFVYTPGRQCVVSGWGSMG----LRYAERLQAAL-IPIINRFDC-----VNSSQ 872

  Fly   202 VHS----TNLCTGPLTGGVSICTSDSGGPLV-----QGNVLIGIVSWGKLPCGQANSPSVYVQVS 257
            ::|    :..|.|.|.||:..|..|||||..     ...||.|::|||. .|.|...|.:|..|:
Worm   873 IYSSMSRSAFCAGYLEGGIDSCQGDSGGPFACRREDGAFVLAGVISWGD-GCAQKKQPGIYTMVA 936

  Fly   258 SFISWISA 265
            .::|||||
Worm   937 PYLSWISA 944

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_001285870.1	Tryp_SPc	35..263	CDD:214473	72/245 (29%)
Phae1	NP_001285870.1	Tryp_SPc	36..266	CDD:238113	75/248 (30%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	75/248 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910