Protein Alignment Phae1 and TMPRSS11B

DIOPT Version :10

• Sequence 1: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_872308.2
• Gene: TMPRSS11B / 132724
• HGNCID: 25398
• Length: 416
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 82/278 - (29%)
• Similarity: 130/278 - (46%)
• Gaps: 43/278 - (15%)

  Fly     1 MLANGQQTKSLASGLLLLLGICRISGVAIGAPEGRVVGGSPAAVNSAPYAVSMQYGGTHYCAASI 65
            ||.|....:.:|:.:        |:|       .::|.|..:...:.|:..|||:.|.|||.||:
Human   165 MLTNNCCGRQVANSI--------ITG-------NKIVNGKSSLEGAWPWQASMQWKGRHYCGASL 214

  Fly    66 LNANWLVTAAHCLTNSNQVLGSTLVAGSIAVDGTASTTQTRSITYFVINDLYTGGTVPYDIGMIY 130
            :::.||::||||....|.....|:..| |.|:   ....||.:...:.::.|:...:..||.::.
Human   215 ISSRWLLSAAHCFAKKNNSKDWTVNFG-IVVN---KPYMTRKVQNIIFHENYSSPGLHDDIALVQ 275

  Fly   131 TPTAFVWSAAVAPVTLP--------SSGVVPTGTANLYGWGSTSTTNTASYPSTLQVATNVPIIS 187
            ......::..:..:.||        :..||.||...||..|        |:|..|| ...:.||.
Human   276 LAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNG--------SFPVILQ-EDFLKIID 331

  Fly   188 LSSCESALGTKGSDVHSTNLCTGPLTGGVSICTSDSGGPLV---QGNV--LIGIVSWGKLPCGQA 247
            ...|.::....|. |..|.||.|.::|....|.:||||||.   ..|:  |:||||||. .||:.
Human   332 NKICNASYAYSGF-VTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGD-GCGKK 394

  Fly   248 NSPSVYVQVSSFISWISA 265
            |.|.||.:|:|:.:||::
Human   395 NKPGVYTRVTSYRNWITS 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	76/243 (31%)
TMPRSS11B	NP_872308.2	SEA	45..142	CDD:460188
		Tryp_SPc	185..413	CDD:238113	76/243 (31%)