Protein Alignment Phae1 and KLK8

DIOPT Version :10

• Sequence 1: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 66/236 - (27%)
• Similarity: 103/236 - (43%)
• Gaps: 14/236 - (5%)

  Fly    31 APEGRVVGGSPAAVNSAPYAVSMQYGGTHYCAASILNANWLVTAAHCLTNSNQVLGSTLVAGSIA 95
            |.|.:|:||.....:|.|:..::..|....|...::..||::|||||....     .|:..|..:
Human    73 AQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPK-----YTVRLGDHS 132

  Fly    96 VDGTASTTQTRSITYFVINDLYTGGTVP---YDIGMIYTPTAFVWSAAVAPVTLPSSGVVPTGTA 157
            :.......|...:...:.:..|....|.   :|:.::.........:.|.|::|......|....
Human   133 LQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKC 197

  Fly   158 NLYGWGSTSTTNTASYPSTLQVATNVPIISLSSCESALGTKGSDVHSTNLCTGPLTGGVSICTSD 222
            .:.||| |.|:...::|.||..| .|.|.....||.|...:.:|   ..:|.|. :.|...|..|
Human   198 TVSGWG-TVTSPRENFPDTLNCA-EVKIFPQKKCEDAYPGQITD---GMVCAGS-SKGADTCQGD 256

  Fly   223 SGGPLVQGNVLIGIVSWGKLPCGQANSPSVYVQVSSFISWI 263
            ||||||....|.||.|||..|||:::.|.||..:..::.||
Human   257 SGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	64/231 (28%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	62/230 (27%)