Protein Alignment Phae1 and PRSS21

DIOPT Version :10

• Sequence 1: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 85/283 - (30%)
• Similarity: 123/283 - (43%)
• Gaps: 35/283 - (12%)

  Fly    12 ASGLLLLLGICRISGV---------AIGAPEG------RVVGGSPAAVNSAPYAVSMQYGGTHYC 61
            |.|.|||..:...:|:         .:..|.|      |:|||..|.:...|:..|::...:|.|
Human     3 ARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVC 67

  Fly    62 AASILNANWLVTAAHCL---TNSNQVLGSTLVAGSIAVDGTASTTQTRSITYFVINDLYTG---- 119
            ..|:|:..|.:|||||.   ::.:...|..:..|.:....:..:.|.....|||.| :|..
Human    68 GVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSN-IYLSPRYL 131

  Fly   120 GTVPYDIGMIYTPTAFVWSAAVAPVTLPSSGVVPTGTANLY--GWGSTSTTNTASYPSTLQVATN 182
            |..||||.::.......::..:.|:.|.:|........:.:  |||..........|.||| ...
Human   132 GNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQ-EVQ 195

  Fly   183 VPIISLSSCESALGTKGS---DVHSTNLCTGPLTGGVSICTSDSGGPLV-QGNVL---IGIVSWG 240
            |.||:.|.| :.|..|.|   |:....:|.|...||...|..||||||. ..|.|   ||:||||
Human   196 VAIINNSMC-NHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWG 259

  Fly   241 KLPCGQANSPSVYVQVSSFISWI 263
             :.||:.|.|.||..:|....||
Human   260 -VGCGRPNRPGVYTNISHHFEWI 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	76/244 (31%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	76/244 (31%)