Protein Alignment Rab6 and RAB5B

DIOPT Version :10

• Sequence 1: NP_477172.1
• Gene: Rab6 / 34636
• FlyBaseID: FBgn0015797
• Length: 208
• Species: Drosophila melanogaster
• Sequence 2: NP_001401387.1
• Gene: RAB5B / 5869
• HGNCID: 9784
• Length: 296
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 80/199 - (40%)
• Similarity: 119/199 - (59%)
• Gaps: 23/199 - (11%)

  Fly     7 GNP----LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWD 67
            |.|    :.:||||.|||.:|||:||:.||:...|....::|||..||::::.|:|.||:.::||
Human    92 GQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWD 156

  Fly    68 TAGQERFRSLIPSYIRDSTVAVVVYDITNTNSFHQTSKWIDDVRTERGSDVIIMLVGNKTDLSDK 132
            ||||||:.||.|.|.|.:..|:|||||||..:|.:...|:.:::.:....::|.|.|||.||::|
Human   157 TAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANK 221

  Fly   133 RQVSTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALP---------------GMD----S 178
            |.|..||.:..|.:.:::|:|||||...||..||..:|..||               |:|    |
Human   222 RMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRGVDLHEQS 286

  Fly   179 TENK 182
            .:||
Human   287 QQNK 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab6	NP_477172.1	Rab6	13..173	CDD:206654	71/159 (45%)
RAB5B	NP_001401387.1	Rab5_related	101..263	CDD:206653	71/161 (44%)