DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab6 and W04C9.5

DIOPT Version :9

Sequence 1:	NP_001285869.1	Gene:	Rab6 / 34636	FlyBaseID:	FBgn0015797	Length:	208	Species:	Drosophila melanogaster
Sequence 2:	NP_490735.3	Gene:	W04C9.5 / 189184	WormBaseID:	WBGene00021027	Length:	369	Species:	Caenorhabditis elegans

Alignment Length:	198	Identity:	50/198 - (25%)
Similarity:	89/198 - (44%)	Gaps:	24/198 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PLRKFKLVFLGEQSVGKTSLITRF------MYDSFDNTYQATIGIDFLSKTM--YLEDRTVRLQL 65
            |::...|...|.::.||.:|::..      :...::|  ::..|.|..||||  .|.:..:.|::
Worm   167 PMQHVVLRVYGSRNSGKKTLLSAINQFATRLVTQYNN--ESNEGDDTSSKTMNFLLNNEQIELEM 229

  Fly    66 WDTAGQER--FRSLIPSYIRDSTVAVVVYDITNTNSFHQTSKWIDDV---RTERGSDVIIMLVGN 125
            ...|..|.  |.|.:..|       .:||::.|..||...:..:..:   :..||:::|  |:||
Worm   230 LLEATLENSPFASSLTMY-------AIVYNVDNRESFVCATDLLSRLLNRKIARGANII--LIGN 285

  Fly   126 KTDLSDKRQVSTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMDSTENKPSEDMQEV 190
            |.||.....||..||...||.....|:|.||:...|:.:|:..:...|....:...:|:..|..:
Worm   286 KIDLKRNTVVSKMEGACLAKVHKCNFVEVSAQYSMNISELWTIILKQLQAPKAELEEPNGWMHRI 350

  Fly   191 VLK 193
            |.:
Worm   351 VTR 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab6	NP_001285869.1	Rab6	13..173	CDD:206654	45/172 (26%)
W04C9.5	NP_490735.3	P-loop_NTPase	171..333	CDD:304359	45/172 (26%)
W04C9.5	NP_490735.3	Ras	177..333	CDD:278499	44/166 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910