DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and SWF1

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_010411.1	Gene:	SWF1 / 851704	SGDID:	S000002533	Length:	336	Species:	Saccharomyces cerevisiae

Alignment Length:	209	Identity:	56/209 - (26%)
Similarity:	84/209 - (40%)	Gaps:	72/209 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   431 YYRAIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNR 495
            ||.|||                  |.:||.::|.|:|||.:|||||...||||.:|.||:|..|.
Yeast   130 YYPAIK------------------CSTCRIVKPARSKHCSICNRCVLVADHHCIWINNCIGKGNY 176

  Fly   496 MWFFLFVLSVAVNCSFTIYFACYCVMIEGFTMLYVLGL----------IEAVVFCGLGWILTCTS 550
            :.|:||::|       .|:..||     .|..|:.:.|          :...:.||      |.:
Yeast   177 LQFYLFLIS-------NIFSMCY-----AFLRLWYISLNSTSTLPRAVLTLTILCG------CFT 223

  Fly   551 ILHACM----------NLTTNEMFNYKRYPYLRDKRGRYQNPFSRGPILNLLE------FFVCLP 599
            |:.|..          .:||||          :||....|.....|.::..|:      ||.|..
Yeast   224 IICAIFTYLQLAIVKEGMTTNE----------QDKWYTIQEYMREGKLVRSLDDDCPSWFFKCTE 278

  Fly   600 DRGDDNDLLLEDNI 613
            .:.|..:.|.:.::
Yeast   279 QKDDAAEPLQDQHV 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	41/131 (31%)
SWF1	NP_010411.1	COG5273	22..336	CDD:227598	56/209 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22883
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000