DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and ZDHHC16

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_006718084.1	Gene:	ZDHHC16 / 84287	HGNCID:	20714	Length:	384	Species:	Homo sapiens

Alignment Length:	206	Identity:	52/206 - (25%)
Similarity:	87/206 - (42%)	Gaps:	48/206 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   332 VVRLLYGEVKKKSRWIPSVSESWGWLFGGAGDSKG----PLFLFLFSVLLWGYPMYMIRAIPITW 392
            |.|..||:|..:|....|        |||:..:..    |::..:.:|:.|...::::..|.:|.
Human    36 VQRWRYGKVCLRSLLYNS--------FGGSDTAVDAAFEPVYWLVDNVIRWFGVVFVVLVIVLTG 92

  Fly   393 NILRRSHYC-----------------FIY--WNAVMWISWAIANRRDPGYIPLSSDAYYRAIKQI 438
            :|:..::.|                 |.|  ||.::.:.                 .||:||...
Human    93 SIVAIAYLCVLPLILRTYSVPRLCWHFFYSHWNLILIVF-----------------HYYQAITTP 140

  Fly   439 PYFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVL 503
            |.:....:.::....:|..|...:|.|..||.:|||||...|||||::.||||..|..:||.|..
Human   141 PGYPPQGRNDIATVSICKKCIYPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCF 205

  Fly   504 SVAVNCSFTIY 514
            .:.:.|.:..|
Human   206 FMTLGCVYCSY 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185	2/3 (67%)
		DHHC	455..567	CDD:334580	26/60 (43%)
ZDHHC16	XP_006718084.1	zf-DHHC	155..312	CDD:279823	26/62 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810