DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and zdhhc5b

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_009289570.1	Gene:	zdhhc5b / 792560	ZFINID:	ZDB-GENE-101117-1	Length:	658	Species:	Danio rerio

Alignment Length:	280	Identity:	77/280 - (27%)
Similarity:	124/280 - (44%)	Gaps:	79/280 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 KKSRWIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAIPITWNILRRSHYCFI-YW 405
            :.||::| ||.:..:|.|..       .|||.....|                |......|| .:
Zfish    21 RPSRYVP-VSAATAFLVGAT-------TLFLCFTCPW----------------LSEKFSSFIPLY 61

  Fly   406 NAVMWI----SWAIANRRDPGYIPLSSDAY-----YRAIKQIPYFDKLKKRNVML-TRLCHSCRC 460
            |.|:::    ::.:|...|||..|.:.:..     :||    |.:..::.|.:.: .:.|.:||.
Zfish    62 NVVVFLFTLANFCMATFMDPGVFPRAEEDEDKEDDFRA----PLYKTVEVRGIQVRMKWCSTCRF 122

  Fly   461 LRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIEGF 525
            .||.|..||.||:.||..||||||::.||:|.||..:||||:||:.|          :.:.:.||
Zfish   123 YRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTV----------HIMDVFGF 177

  Fly   526 TMLYV------LGLIEA----VVFC--GLGWI----LTCTSILHACMNLTTNEMFNYKRYPYLRD 574
            ::||:      |.|:::    .|.|  ||.::    ||...::......||||...
Zfish   178 SLLYILHHTKQLDLVQSGVTMAVMCVAGLFFVPVAGLTGFHVVLVARGRTTNEQVT--------- 233

  Fly   575 KRGRYQ---NPFSRGPILNL 591
              |:::   |||:.|...|:
Zfish   234 --GKFRGGVNPFTHGCFKNI 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	46/127 (36%)
zdhhc5b	XP_009289570.1	DHHC	110..235	CDD:396215	46/145 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900