DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and zdhhc2

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_012820452.1	Gene:	zdhhc2 / 779681	XenbaseID:	XB-GENE-947256	Length:	367	Species:	Xenopus tropicalis

Alignment Length:	312	Identity:	77/312 - (24%)
Similarity:	119/312 - (38%)	Gaps:	93/312 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   340 VKKKSR----WIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAIPITW-NILRR-- 397
            |:::.|    |||                    .||:..::.|.|..|:|:...:|. ||..:
Frog     9 VRRRCRRCLYWIP--------------------VLFISIIVCWSYYAYVIQLCIVTMDNIAEKIL 53

  Fly   398 ---------SHYCFIYWNAVMWISWAIAN------------RRDP-GYIPLSSDAYYRAIKQIPY 440
                     .|:.:.||..:..:....|.            .|:| |  ....|...|..|.:|.
Frog    54 CLIAYHFFLLHFVWSYWKTIFTLPMNPAKEFHLSYSDKELLEREPRG--ESQQDILRRLAKDLPV 116

  Fly   441 FDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSV 505
            :.:.....:   |.|..|:.::|.|..||.||::|:...|||||::.||||..|..:|.||:
Frog   117 YTRTMSGAI---RYCDRCQLVKPDRCHHCSVCDKCILKMDHHCPWVNNCVGFSNYKFFLLFL--- 175

  Fly   506 AVNCSFTIYFACYCVMI-----EGFTMLYVLGL--------IEAVVFCGLGWILTCTSIL--H-- 553
                   .|...||:.|     :.|...:..||        |..:.|....:.::.:|:.  |
Frog   176 -------AYSLLYCLFIVATDLQYFVKFWTNGLPDTQAKFHIMFLFFAAAMFSVSLSSLFGYHCW 233

  Fly   554 -ACMNLTTNEMFNYKRYPYLRDKRGRYQNPFSRGPILNLLEFFVCLPDRGDD 604
             .|.|.:|.|.|   |.|..|  .|..:|.||.|...||.:.|      ||:
Frog   234 LVCKNRSTLEAF---RAPVFR--HGTDKNGFSLGFSKNLRQVF------GDE 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	38/129 (29%)
zdhhc2	XP_012820452.1	DHHC	19..294	CDD:388695	75/302 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910