DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and Zdhhc20

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_006519721.1	Gene:	Zdhhc20 / 75965	MGIID:	1923215	Length:	475	Species:	Mus musculus

Alignment Length:	309	Identity:	76/309 - (24%)
Similarity:	112/309 - (36%)	Gaps:	93/309 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 GWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAIPITWN----------ILRRSHYCFI--YWNA 407
            ||:         |: ||:..|::|.|..|::.....|.:          .|...|..|:  .|:.
Mouse   110 GWV---------PV-LFITFVVVWSYYAYVVELCVSTISRTGEKGKTVVYLVAFHLFFVMFVWSY 164

  Fly   408 VMWISWAIANRRDPGYIPLSSDAYY--------------RAIKQIPYFDKLKKRNVMLTRLCHSC 458
            .|.|..:.|:.....|:..|....|              ||.:.:|.:.....:.:   |.|..|
Mouse   165 WMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQDILRRAARDLPIYTTSASKAI---RYCEKC 226

  Fly   459 RCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIE 523
            :.::|.||.||..|:|||...|||||::.||||..|..:|.||:|          |...||:.:.
Mouse   227 QLIKPDRAHHCSACDRCVLKMDHHCPWVNNCVGFTNYKFFMLFLL----------YSLLYCLFVA 281

  Fly   524 GFTMLY----------------------VLGLIEA---VVFCGLGWILTCTSIL----HAC---- 555
            ...:.|                      ||....|   |:|......:...|:|    :.|
Mouse   282 ATVLEYFIKFWTLCRRKSTENCPKNEPTVLNFPSAKFHVLFLFFVSAMFFVSVLSLFSYHCWLVG 346

  Fly   556 MNLTTNEMFNYKRYPYLRDKRGRYQNPFSRGPILNLLEFFVCLPDRGDD 604
            .|.||.|.|....:.|..|..|     ||.|...|..:.|      ||:
Mouse   347 KNRTTIESFRAPMFSYGIDGNG-----FSLGCSKNWRQVF------GDE 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	42/144 (29%)
Zdhhc20	XP_006519721.1	DHHC	111..411	CDD:388695	75/308 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810