DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and Zdhhc11

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_081980.1	Gene:	Zdhhc11 / 71164	MGIID:	1918414	Length:	347	Species:	Mus musculus

Alignment Length:	290	Identity:	77/290 - (26%)
Similarity:	114/290 - (39%)	Gaps:	85/290 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   328 QHQDVVRLLYGEVKKKSRWIPSVSE----SWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAI 388
            |..:|.:.|...:.:.:.|.|.:..    ||             :.....|::.:|   ..|..:
Mouse    19 QENNVKKFLPRPLSRVNGWSPPLHSFQAISW-------------ITYLAMSIVTFG---IFIPFL 67

  Fly   389 PITW----NILRRSHYCFIYWNAVMWISWAIANRRDPGYIPLSSDAYYRAIKQ----IPYFDKLK 445
            |.:|    ||:...  .||:...|..|:..|    ||      :|...|..|.    :|.||:.|
Mouse    68 PYSWKYAANIVMGG--VFIFHLIVHLIAITI----DP------ADTNVRLKKDYTQPVPAFDRSK 120

  Fly   446 KRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCS 510
            ..:|:..:.||.|......:||||..||:|||.|||||.::.||||.||..:||..|.|.||...
Mouse   121 HTHVIQNQYCHLCEVTASKKAKHCSACNKCVSGFDHHCKWLNNCVGRRNYWFFFWSVASAAVGIL 185

  Fly   511 FTIYFACY-C------------------VMIEGFTMLY-----------------VLGLIEAVV- 538
            ..:...|| |                  ::.|...:|:                 |:.|:.|:.
Mouse   186 GVMIILCYICIQYFVNPDELRTDPLYKEIISENTWLLFLSLWPVPVKTPIVLSIAVMALLLAIAS 250

  Fly   539 FCGLGWILTCTSILHACMNLTTNEM--FNY 566
            |..||.:|    |.|  :.|.|..|  |:|
Mouse   251 FVMLGHLL----IFH--LYLITKNMSTFDY 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185	2/7 (29%)
		DHHC	455..567	CDD:334580	48/151 (32%)
Zdhhc11	NP_081980.1	zf-DHHC	123..277	CDD:279823	49/158 (31%)
Zdhhc11	NP_081980.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	291..332
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900