DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and Zdhhc24

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_081752.2	Gene:	Zdhhc24 / 70605	MGIID:	1917855	Length:	284	Species:	Mus musculus

Alignment Length:	251	Identity:	54/251 - (21%)
Similarity:	86/251 - (34%)	Gaps:	58/251 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   405 WNAVMWISWAIANRRDPGYIPLS--SDAYYRAIKQIPYFDKLKK-----------RNVMLT---- 452
            |.||:.:..|......||..||.  :.|...|:......:.|..           |.|||.
Mouse    25 WAAVVVLELAYVMVLGPGPPPLGPLARALQLALAAYQLLNLLGNVVLFLRSDPSIRGVMLAGRGL 89

  Fly   453 ----RLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRN-RMWFFLFVLSVAVNCSFT 512
                ..|:.|:...|.|:.||..|..|:...||||..:..|||..| |.:..|.:.|..|....:
Mouse    90 GQGWAYCYQCQSQVPPRSGHCSACRVCILRRDHHCRLLGCCVGFHNYRPFLCLLLHSAGVLLHIS 154

  Fly   513 IYFA-CYCVMIEGFTMLYVLGLIEAVVFCGLGWIL------------------TCTS-------- 550
            :... ....:::..:.||.:.|:.      |.|::                  ||.:
Mouse   155 VLLGPALSALLQAHSALYTVALLL------LPWLMLLTGKVSLAQFALAFVVDTCVAGALLCGAG 213

  Fly   551 -ILHACMNLTTNEMFNYKRYPYLRDKRGRYQNPFSRGPILNLLEF--FVCLPDRGD 603
             :.|..:.|.....:.:.|..:..|....:....:.||...|:.|  |:..|..||
Mouse   214 LLFHGMLLLRGQTTWEWARGHHCYDLGTCHNLQAALGPRWALVWFWPFLASPLPGD 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	29/140 (21%)
Zdhhc24	NP_081752.2	zf-DHHC	95..232	CDD:279823	29/142 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900