DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and CG18810

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_652670.2	Gene:	CG18810 / 59171	FlyBaseID:	FBgn0042133	Length:	300	Species:	Drosophila melanogaster

Alignment Length:	301	Identity:	70/301 - (23%)
Similarity:	107/301 - (35%)	Gaps:	90/301 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   369 FLFLFSVLLWGYPMYMIRAIPITWNILRRSHYCFIYWNAVMWISWAIANRRDPGYI--------- 424
            |||||  :|.|.|.                    ||:..:..|...:::...|||:
  Fly    18 FLFLF--ILCGLPA--------------------IYYVLMEIILPELSDYWSPGYVFQLLLGLFL 60

  Fly   425 ---PLSSDAYYRAIKQIPYFD-KLKKRNVMLTR------LCHSCRCLRPLRAKHCRVCNRCVSYF 479
               .:|:  |...|...|..| ||.|..::..:      .|..|..|.|.|::|||.|..||...
  Fly    61 FSNVMSN--YVMCILVDPSIDPKLMKNQLVRGQHSEDWHECDKCGILAPPRSRHCRKCGVCVLMR 123

  Fly   480 DHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTI----------------------------YFA 516
            ||||.|...|:|..|..:||.|::...::|..::                            ||.
  Fly   124 DHHCFFTGCCIGHENYRYFFYFLIYFFLSCMISLTSSSIFIYVLHGGRYQLFMLTHPAPNSAYFN 188

  Fly   517 CYCVMIEGFTMLYVLGLIEAVVFCGLGWILTCTSILHA---------CMNLTTNEMFNYKRYPYL 572
            ...:.|..|.:..:..|:..:||. |.||..|.:...|         |.:      |..:..|:.
  Fly   189 SLIIRIIYFKLPDIYELVFTLVFV-LLWIGVCVATYVAYDQWSRGYFCYD------FELQNIPFD 246

  Fly   573 RDKRGRYQNPFSRGPILNLLEFFVCLPDRGDDNDLLLE-DN 612
            |..|..::....|......:..||  |.:.|.:...|: ||
  Fly   247 RKLRRNFKTFLGRRMKWTWISGFV--PSQLDHDGFDLDPDN 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	37/148 (25%)
CG18810	NP_652670.2	zf-DHHC	92..>138	CDD:303066	18/45 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467591
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740