DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and zdhhc14

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001038652.1	Gene:	zdhhc14 / 569667	ZFINID:	ZDB-GENE-040724-21	Length:	513	Species:	Danio rerio

Alignment Length:	279	Identity:	74/279 - (26%)
Similarity:	108/279 - (38%)	Gaps:	84/279 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   366 GPLFLFLFSVLL---WGYPMYMIRAIPITWNILRRSHYCFIYWNAVMWISWAIANR--RDPGYIP 425
            |.||:|:..:||   :..|..:.||.|.....:.|.               ..||.  ..|||.|
Zfish    98 GVLFVFVMGMLLRASFSDPGVLPRATPEEAADIERQ---------------IDANNGPSGPGYRP 147

  Fly   426 LSSDAYYRAIKQIPYFDKLKKRNVMLT------RLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCP 484
                             ..:.|.|::.      :.|.:|:..||.||.||.:|:.||..||||||
Zfish   148 -----------------PPRTREVLINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCP 195

  Fly   485 FIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIE----------------------GFTM 527
            ::.||||.||..:|:||:||::....|...|....|::.                      |...
Zfish   196 WVGNCVGRRNYRFFYLFILSLSFLTIFIFAFVITHVILNALRKALALSTAADFEAVQKDPTGLAF 260

  Fly   528 LY-----VLGLIEAVVFCGLGWILTCTSILHACM---NLTTNE----MFNYKRYPYLRDKRGRYQ 580
            |.     :|.::|.||.....|.:...|..|..:   |.||||    .::.||      .:|.|
Zfish   261 LVLSKTALLDVLEVVVCFFSVWSIVGLSGFHTYLISSNQTTNEDIKGSWSSKR------GKGNY- 318

  Fly   581 NPFSRGPILNLLEFFVCLP 599
            ||:|.|..:......:|.|
Zfish   319 NPYSYGNFITNCCSALCGP 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	45/145 (31%)
zdhhc14	NP_001038652.1	zf-DHHC	163..306	CDD:279823	45/142 (32%)
zdhhc14	NP_001038652.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	348..369
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910