DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and zdhhc12

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_012825930.1	Gene:	zdhhc12 / 550061	XenbaseID:	XB-GENE-1216126	Length:	276	Species:	Xenopus tropicalis

Alignment Length:	276	Identity:	76/276 - (27%)
Similarity:	113/276 - (40%)	Gaps:	70/276 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   364 SKGPLFLFLFSVLLWGYPMYMIRAIPITWNILRRSHYCFI----------YWNAVMWISWAI--- 415
            |.|.|...:.:||.||..:.:         .|..:...||          .|..:..:|:.:
Frog     7 SAGFLVRTVHTVLTWGVTLVL---------FLHDTDIFFICHSDLYHQENQWKLLQPLSFGLLVL 62

  Fly   416 --------ANRRDPGYI-------PLSSDAYYRAIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLR 465
                    .:..||||:       ||.:  |......||     :..:.|..|.|..|...:|:|
Frog    63 CSVLLYFAVSLMDPGYVLSDCNKKPLPT--YLEQGVMIP-----EAPSGMRLRRCGYCLLQQPIR 120

  Fly   466 AKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIEGFTM--- 527
            |:||:.|:.||..||||||:|.||||.||...|.|:     :...|.:....:.:...||..
Frog   121 ARHCKTCHHCVRRFDHHCPWIENCVGERNHPLFMLY-----LGVQFLVLLWAFRLTWSGFQFEAS 180

  Fly   528 ----LYV-LGLIEAVVFCGL-----GWILTCTSILHACMNLTTNEMFNYKRYPYLRDKRGRYQ-- 580
                |.| :.|:.|.:..|:     ..:|.|...|.:| |:||.|..::.|..||:    .|.
Frog   181 WTEWLKVNIFLLLAFILTGIFTFVVALLLGCHCYLISC-NVTTWEFMSHHRISYLK----HYDSD 240

  Fly   581 -NPFSRGPILNLLEFF 595
             |||.:|...||.:||
Frog   241 TNPFDKGIARNLWDFF 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	41/124 (33%)
zdhhc12	XP_012825930.1	DHHC	105..228	CDD:366691	43/128 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000