DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and zdhhc2

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_021336686.1	Gene:	zdhhc2 / 541365	ZFINID:	ZDB-GENE-050320-58	Length:	374	Species:	Danio rerio

Alignment Length:	332	Identity:	74/332 - (22%)
Similarity:	115/332 - (34%)	Gaps:	114/332 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 DVVRLLYGEVKKKSRWIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIR-AIPITWNI 394
            |..|:||        |||                    .||:..::.|.|..|::: .|....|:
Zfish    10 DCWRVLY--------WIP--------------------VLFISLIVAWSYYAYVVQLCIETIENM 46

  Fly   395 LRRSHYCFIY---WNAVMWISWAI------------------------ANRRDPGYIPLSSDAYY 432
            ..::.|..||   :...:|..|..                        .:||:.     ..:...
Zfish    47 GEKTVYLLIYHLLFLMFVWSYWQTIYSKPMNPLKEFHLSHVDKELLEREDRRES-----QQEILR 106

  Fly   433 RAIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMW 497
            |..|.:|.:.:.....:   |.|..|..|:|.|..||..|:.|:...|||||::.||||..|..:
Zfish   107 RIAKDLPIYTRTMSGAI---RYCDRCLLLKPDRCHHCSACDMCILKMDHHCPWVNNCVGFANYKF 168

  Fly   498 FFLFVLSVAVNCSFTI-----YFACYCVMIEGFT----MLYVLGLIE------------------ 535
            |.||:....:.|.|..     ||..:.. ::|.|    :.|:.||.:
Zfish   169 FMLFLAYSLLYCLFVTATDMQYFIQFWT-VDGKTHDRLIQYLNGLPDTQAKFHIMFLFFAASTFS 232

  Fly   536 ---AVVFCGLGWILTCTSILHACMNLTTNEMFNYKRYPYLRDKRGRYQNPFSRGPILNLLEFFVC 597
               |.:|....|::        |.|.:|.|.|....:.:..||.|     ||.|...|..:.|
Zfish   233 VSLAFLFAYHCWLV--------CKNRSTLEAFRAPAFQHGTDKNG-----FSLGAYKNFRQVF-- 282

  Fly   598 LPDRGDD 604
                ||:
Zfish   283 ----GDE 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185	2/4 (50%)
		DHHC	455..567	CDD:334580	39/141 (28%)
zdhhc2	XP_021336686.1	zf-DHHC	11..305	CDD:327686	73/331 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810