DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and Zdhhc14

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001034432.1	Gene:	Zdhhc14 / 499014	RGDID:	1565877	Length:	489	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	70/250 - (28%)
Similarity:	107/250 - (42%)	Gaps:	61/250 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   387 AIPITWNILRRSHYCFIYWNAVMWISWAIANRRDPGYIPLSS-DAYYRAIKQIP---------YF 441
            |||:...||     .|.....::..|::     |||.:|.:: |......:||.         |.
  Rat    93 AIPVVGGIL-----FFFVMGTLLRTSFS-----DPGVLPRATPDEAADLERQIDIANGTSSGGYR 147

  Fly   442 DKLKKRNVMLT------RLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFL 500
            ...:.:.|::.      :.|.:|:..||.||.||.:|:.||..||||||::.||||.||..:|::
  Rat   148 PPPRTKEVIINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVEQFDHHCPWVGNCVGKRNYRFFYM 212

  Fly   501 FVLSVAVNCSFTIYFACYCVMIEGFTMLYVL-----------------GLIEAVVFCGLGWILTC 548
            |:||:    ||...|      |..|.:.:|:                 .::|||:.....|.:..
  Rat   213 FILSL----SFLTVF------IFAFVITHVIHRSQQKGFLDALKDSPASVLEAVICFFSVWSIIG 267

  Fly   549 TSILHACM---NLTTNEMFNYKRYPYLRDKRGRYQ-NPFSRGPILNLLEFFVCLP 599
            .|..|..:   |.||||.....    ..:|||:.. ||:|.|.|.......:|.|
  Rat   268 LSGFHTYLISSNQTTNEDIKGS----WSNKRGKENYNPYSYGNIFTNCCVALCGP 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	44/131 (34%)
Zdhhc14	NP_001034432.1	DHHC	164..287	CDD:396215	44/132 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810