DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and Zdhhc11

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_038942712.1	Gene:	Zdhhc11 / 499000	RGDID:	1564281	Length:	364	Species:	Rattus norvegicus

Alignment Length:	245	Identity:	73/245 - (29%)
Similarity:	103/245 - (42%)	Gaps:	57/245 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   328 QHQDVVRLLYGEVKKKSRWIPSVSE----SWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAI 388
            |..:|.:||...:.:.:.|.|.:..    ||            ..:|.: |::.:|   ..|..:
  Rat    19 QENNVKKLLPRPLSRVNGWSPPLHSFQAISW------------TTYLAM-SIVTFG---IFIPFL 67

  Fly   389 PITWNILRRSHYCFIYWNAVM-------WISWAIANRRDPG--YIPLSSDAYYRAIKQIPYFDKL 444
            |.:|....         ||||       .:...||...||.  .:.|..|    .::.:|.||:.
  Rat    68 PTSWKYAA---------NAVMGGVFMFHLVVHLIAITIDPADTNVRLKKD----YLEPVPTFDRS 119

  Fly   445 KKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVA--- 506
            |..:|:..:.||.|......:||||..||:|||.|||||.::.||||.|| .|||.|.::.|
  Rat   120 KHAHVIQNQYCHLCEVTVSKKAKHCSSCNKCVSGFDHHCKWLNNCVGKRN-YWFFFFSVASAAFG 183

  Fly   507 ---VNCSFTIYFACYCVMIEGFTM--LYVLGLIEAVVFCGLGWILTCTSI 551
               |.......|..|.|...|..|  ||.    .|.|:.|.||  ||.|:
  Rat   184 LLGVLIILLYIFIQYFVNPNGLRMDPLYK----GAAVWIGAGW--TCLSV 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185	2/7 (29%)
		DHHC	455..567	CDD:334580	44/105 (42%)
Zdhhc11	XP_038942712.1	DHHC	123..294	CDD:396215	45/112 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900