DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and zdhhc3a

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001002725.1	Gene:	zdhhc3a / 436998	ZFINID:	ZDB-GENE-040718-484	Length:	316	Species:	Danio rerio

Alignment Length:	277	Identity:	62/277 - (22%)
Similarity:	114/277 - (41%)	Gaps:	67/277 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   309 DLEPRDKNGKTPIMLAQAHQHQDVVRLLYGEVKKKSRWIPSVSESWG-------WLFGGAGDSKG 366
            |:|.:....:.|..|...|:.|:            |.|.  :.::.|       |
Zfish    10 DVERQASGLQPPQCLPSCHERQN------------SMWF--IKDACGIVCAIITW---------- 50

  Fly   367 PLFLFLFS--VLLWGYPMYMIRAIPITWNILRRSHYCFIYWNAVMWISWAIANR---RDPGYIPL 426
              ||..|:  |:|:   :.:|.:..:|::::..:     .:|::.:::.|...|   .|||.:|.
Zfish    51 --FLVFFAEFVVLF---VMLIPSKNLTYSLVNGT-----LFNSLAFLALASHFRAMCTDPGAVPK 105

  Fly   427 SSDAYYRAIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVG 491
            .:     |.|:  |.:.|:.:...:...|..|..::|.||.||.||.||:...|||||::.||||
Zfish   106 GN-----ATKE--YIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVG 163

  Fly   492 LRNRMWFFLFVLSVA--------------VNCSFTIYFACYCVMIEGFTMLYVLGLIEAVVFCGL 542
            ..|:.:|.||.:.:.              :||....:..|.........:|.:|...|.::|...
Zfish   164 ENNQKYFVLFTMYICLISLHSLVMVVFHFLNCFEDDWTKCSTFSPPATVILLILLCFEGLLFLIF 228

  Fly   543 GWILTCTSILHACMNLT 559
            ..::..|.:...|.:.|
Zfish   229 TSVMFGTQVHSICTDET 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786	2/4 (50%)
		Ank_4	283..336	CDD:316185	6/26 (23%)
		DHHC	455..567	CDD:334580	34/119 (29%)
zdhhc3a	NP_001002725.1	zf-DHHC	127..251	CDD:279823	34/119 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810