DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and zdhhc7

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001002602.1	Gene:	zdhhc7 / 436875	ZFINID:	ZDB-GENE-040718-346	Length:	299	Species:	Danio rerio

Alignment Length:	305	Identity:	72/305 - (23%)
Similarity:	123/305 - (40%)	Gaps:	76/305 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   323 LAQAHQHQDVVRLLYG---EVKKKSRWIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYM 384
            |....|||.   ||.|   ||.....|.  :.:|.|               .:.:.:.|...||.
Zfish     8 LRDVEQHQP---LLSGGEEEVTAGRVWF--IQDSCG---------------MVCAFMTWSLVMYA 52

  Fly   385 IRAIPITWNILRRSHYCFIYWNAVMWISWAI----ANRR----DPGYIPLSSDAYYRAIKQIPYF 441
            ...:.... :|...::.:...|.|.:...|:    ::.|    |||.:|..:     |.|:  |.
Zfish    53 EFVVNFVM-LLPSKNFWYTLINGVAFNFLAVLALTSHLRTMLTDPGAVPKGN-----ATKE--YM 109

  Fly   442 DKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVA 506
            :.|:.:...:...|..|..::|.||.||.:|.||:...|||||::.||||..|:.:|.||.:.:|
Zfish   110 ESLQLKPGEVIYKCPKCCSIKPERAHHCSICKRCIRKMDHHCPWVNNCVGENNQRFFVLFTMYIA 174

  Fly   507 VNCSFTIYFACY-------CVMIE-----GFT-----MLYVLGLIEAVVFCGLGWILTCTSILHA 554
               |.:::..|.       ||.::     .|:     ||.:...:||::|.....::..|.|...
Zfish   175 ---SISLHALCLSGFHFFTCVKVQWNECSDFSPPVAVMLLIFLCLEALLFLTFTAVMFGTQIHSI 236

  Fly   555 CMNLTTNEMFNYKRYPYLRDKRGRYQ---------------NPFS 584
            |.:.|..|....::..:  ::|.|:.               |||:
Zfish   237 CNDETEIERLKNEKPTW--ERRVRWDGMKAVFGGPPSLLWFNPFA 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185	4/12 (33%)
		DHHC	455..567	CDD:334580	39/128 (30%)
zdhhc7	NP_001002602.1	DHHC	122..249	CDD:396215	39/129 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810