DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and zdhhc16b

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_009304660.1	Gene:	zdhhc16b / 393316	ZFINID:	ZDB-GENE-040426-1301	Length:	382	Species:	Danio rerio

Alignment Length:	293	Identity:	67/293 - (22%)
Similarity:	109/293 - (37%)	Gaps:	94/293 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 LFLFLFSVLLWGYPMYMIRAIPITWNILRRSHYCFIYWNAVMWISWAIANRRDPGYIPLSSDAYY 432
            ::|.:..::...||:|.     |.|      |.|:.:||.:|.:.                 .||
Zfish    96 VYLCVLPIIFSSYPVYW-----ILW------HLCYGHWNLLMVVF-----------------HYY 132

  Fly   433 RAIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMW 497
            :|....|.|...:|.::....:|..|...:|.|..||.:||||:...|||||::.||||..|..:
Zfish   133 KATTTQPGFPPQEKTDIPTVTICKKCIVPKPARTHHCSICNRCILKMDHHCPWLNNCVGHFNHRY 197

  Fly   498 FFLFVLSVAVNCSFTIYFACYC------VMIEGFTML----YVLGLIEAVVFCGLG--------- 543
            ||.|.|.:.:.|       .||      :.::.:..:    |..|..:.....|.|
Zfish   198 FFSFCLFMTMGC-------VYCSISAKDMFLDAYNAIESGRYKGGASQGEAVPGAGLIYISFQHQ 255

  Fly   544 ------------------------WILTCT--------SILHACMNLTTNEM-----FNYKRYPY 571
                                    |:||.:        ::.||.: :|..|.     .|.|....
Zfish   256 SSYQTPPPAFTHQERMVHKSLVYLWVLTSSVAVALGALTLWHAIL-ITRGETSVERHINRKERRR 319

  Fly   572 LRDKRGRYQNPFSRGPILNLLEFFVCLPDRGDD 604
            |:.:...::||:..|.|.|...||..  ::|.|
Zfish   320 LKLRGKLFRNPYHHGRINNWRIFFGV--EKGSD 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	39/167 (23%)
zdhhc16b	XP_009304660.1	zf-DHHC	83..>206	CDD:327686	41/137 (30%)
zdhhc16b	XP_009304660.1	zf-DHHC	154..310	CDD:307600	38/163 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810