DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001032741.1	Gene:	Zdhhc6 / 361771	RGDID:	1304657	Length:	413	Species:	Rattus norvegicus

Alignment Length:	179	Identity:	44/179 - (24%)
Similarity:	75/179 - (41%)	Gaps:	45/179 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   366 GPLF----------LFLFSVLLWGYPMYMIRA-----IPITWNILRRSHYCFIYWNAVMWISWAI 415
            ||:.          :.:...:||.:|::....     :.|.|.::    ..:.|:||:.
  Rat    23 GPIIALGVIAICSTMAMIDSVLWYWPLHTTGGSVNFIMLINWTVM----ILYNYFNAMF------ 77

  Fly   416 ANRRDPGYIPLSSDAYYRAIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFD 480
               ..||::|..             :.....::.|..:.|..|:..:..|:.|||.|||||...|
  Rat    78 ---AGPGFVPRG-------------WKPENPQDSMYLQYCKVCQAYKAPRSHHCRKCNRCVMKMD 126

  Fly   481 HHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIEGFTMLY 529
            ||||:|.||.|.:|...|.||:|...:.|:    .|.:..::..:|.||
  Rat   127 HHCPWINNCCGHQNHASFTLFLLLAPLGCT----HAAFIFVMTMYTQLY 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	30/75 (40%)
Zdhhc6	NP_001032741.1	DHHC	95..241	CDD:396215	31/81 (38%)
Zdhhc6	NP_001032741.1	SH3_2	317..394	CDD:400139
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900