DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and spe-10

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001021339.1	Gene:	spe-10 / 3565514	WormBaseID:	WBGene00004964	Length:	351	Species:	Caenorhabditis elegans

Alignment Length:	263	Identity:	58/263 - (22%)
Similarity:	100/263 - (38%)	Gaps:	77/263 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 GWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAIPITWNI---LRRSHYCFIYWNAVMWISWAIA 416
            ||:.....:    :.||:..:||| :.:||...:.|.:.:   ::.:.|..:.....:...|::|
Worm    22 GWILTRCLN----VLLFIQLILLW-WSLYMYVTVTIGYYVQSTIQATIYLIVGSFLFVMSMWSLA 81

  Fly   417 NR--RDPGYIPLSSDAYYRAIKQIPYFDKLK---------------------KRNVMLTRLCHSC 458
            ..  ...|.:|    ..||..|::.  |:||                     ::|.:|..:|..|
Worm    82 KTLFTRVGRVP----ERYRPSKELE--DRLKAVTPMEKNRYVVEKSTPEQLAQQNTILEEMCTYC 140

  Fly   459 R-----------------C--LRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLS 504
            :                 |  ::|.||:||..|.:|...:|||||:|..||...|..:|.|::
Worm   141 KVVVAECDQVGRLKYCYECGHIKPDRARHCSSCGKCCIKYDHHCPWINMCVTHVNYKYFLLYI-- 203

  Fly   505 VAVNCSFTIYFACYCVMIEGFTMLYVLGLIEAVV--FCGLGWILTCTSILHACMNLTTNEMFNYK 567
              :..||.:|:             |:|..:|..|  |....|.......|....:.....:|.|
Worm   204 --IYTSFLVYW-------------YLLTSLEGAVRYFINQQWTDELGKFLFYLFSFIVGGVFGY- 252

  Fly   568 RYP 570
             ||
Worm   253 -YP 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	32/132 (24%)
spe-10	NP_001021339.1	zf-DHHC	151..277	CDD:279823	33/123 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810