DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and zdhhc8b

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_840089.2	Gene:	zdhhc8b / 352941	ZFINID:	ZDB-GENE-030407-3	Length:	751	Species:	Danio rerio

Alignment Length:	211	Identity:	62/211 - (29%)
Similarity:	102/211 - (48%)	Gaps:	54/211 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   405 WNAVMWI----SWAIANRRDPGYIPLS-----SDAYYRAIKQIPYFDKLKKRNVML-TRLCHSCR 459
            :|.::::    ::::|...|||..|.:     .|..:||    |.:..::.:.:.: .:.|.:|.
Zfish    50 YNGIVFLFVLANFSMATFMDPGVFPRADEDEDKDDDFRA----PLYKNVEIKGIQVRMKWCATCH 110

  Fly   460 CLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIEG 524
            ..||.|..||.||:.||..||||||::.||:|.||..:||||:||::|          :.|.:..
Zfish   111 FYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLSV----------HMVGVFS 165

  Fly   525 FTMLYVLGLIEA----------VVFC--GLGWI----LTCTSILHACMNLTTNEMFNYKRYPYLR 573
            |.:|::|..:|.          ||.|  ||.:|    ||...::......||||...
Zfish   166 FGLLFMLHHLETLSALHTTVTLVVMCVTGLFFIPVMGLTGFHMVLVARGRTTNEQVT-------- 222

  Fly   574 DKRGRYQ---NPFSRG 586
               |:::   |||:||
Zfish   223 ---GKFRGGVNPFTRG 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	46/127 (36%)
zdhhc8b	NP_840089.2	zf-DHHC	99..224	CDD:279823	46/145 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..346
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	437..461
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	633..659
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	666..685
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	703..736
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900