DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Patsas and Dnz1

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_477449.1	Gene:	Dnz1 / 34503	FlyBaseID:	FBgn0027453	Length:	276	Species:	Drosophila melanogaster

Alignment Length:	262	Identity:	63/262 - (24%)
Similarity:	101/262 - (38%)	Gaps:	100/262 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 IRAIPITWNILRRSHYCFIYWNAV------MWISW------------AIANRR----DPGYIPLS 427
            |..:.:|:..:..:.|..|.|..:      :|:|:            |:::.:    |||.:||.
  Fly    10 IACLVVTYGAVLYADYVVIRWIILTTMPGSLWMSFHVVLFNTVVFLLAMSHSKAVFSDPGTVPLP 74

  Fly   428 SDAYYRAIKQIPYFD--KLKKRN-------VMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHC 483
            ::       ::.:.|  ...|.|       .....:|..|...||.||.|||:|.||:...||||
  Fly    75 AN-------RLDFSDLHTTNKNNPPPGNGHSSEWTVCTRCETYRPPRAHHCRICKRCIRRMDHHC 132

  Fly   484 PFIYNCVGLRNRMWFFLFVLSVAV------------------NCSFTI----------------- 513
            |:|.||||.||:.:|..|::.||:                  .||..:
  Fly   133 PWINNCVGERNQKYFLQFLIYVALLSLYSIALIVGSWVWPCEECSQNVIETQLRMIHSVILMLVS 197

  Fly   514 -YFACY--CVMIEGF-TMLYVLGLIEAV------------------VFCGLG----WILTCTSIL 552
             .|..:  .:|::.. .:||....:||:                  || |.|    |:|.|||:.
  Fly   198 ALFGLFVTAIMVDQLHAILYDETAVEAIQQKGTYRPNRRKYQLLADVF-GRGHPALWLLPCTSLN 261

  Fly   553 HA 554
            ||
  Fly   262 HA 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	47/161 (29%)
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	36/130 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467592
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22883
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840