DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and Zdhhc3

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_038937239.1	Gene:	Zdhhc3 / 301081	RGDID:	1309041	Length:	350	Species:	Rattus norvegicus

Alignment Length:	347	Identity:	78/347 - (22%)
Similarity:	139/347 - (40%)	Gaps:	90/347 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   321 IMLAQAHQHQDVVRLLYGEVKKKSRWIP-----SVSESWGWLFGGAGDSKGPLFLFLFSVLLWGY 380
            :||...|..:|:.|  ..|..:..:..|     .|...| ::..|.|.:...:..||  ||...:
  Rat     1 MMLIPTHHFRDIER--KPEYLQPEKCAPPPFPGPVGTMW-FIRDGCGIACAIVTWFL--VLYAEF 60

  Fly   381 PMYMIRAIP---ITWNILRRSHYCFIYWNAVMWISWAI---ANRRDPGYIPLSSDAYYRAIKQIP 439
            .:..:..||   ..::|:..     |.:|.:.:::.|.   |...|||.:|..:     |.|:
  Rat    61 VVLFVMLIPSRDYAYSIING-----IVFNLLAFLALASHCRAMLTDPGAVPKGN-----ATKE-- 113

  Fly   440 YFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLS 504
            :.:.|:.:...:...|..|..::|.||.||.||.||:...|||||::.||||..|:.:|.||.:.
  Rat   114 FIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMY 178

  Fly   505 VAVNCSFTIYFACYCVMIEGF---------------------TMLYVLGLIEAVVFCGLGWILTC 548
            :|:       .:.:.:::.||                     .:|.:|...||::|.....::..
  Rat   179 IAL-------ISLHALIMVGFHFLHCFEEDWTKCSSFSPPTTVILLILLCFEALLFLIFTSVMFG 236

  Fly   549 TSILHACMNLTTNEMFNYKRYPYLRDKRGRYQ---------------NPFSRGPILNLLEFFVCL 598
            |.:...|.:.|..|.....:.|  |::.|.::               |||:|          .|.
  Rat   237 TQVHSICTDETGIERLQRSKQP--REQSGSWKSVQEAFGGEFSLNWFNPFTR----------PCQ 289

  Fly   599 PDRGDDNDLLLE-------DNI 613
            |:...|..|:.:       ||:
  Rat   290 PEIPIDKGLVRQVSSLSNMDNV 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185	5/14 (36%)
		DHHC	455..567	CDD:334580	36/132 (27%)
Zdhhc3	XP_038937239.1	DHHC	128..253	CDD:396215	36/131 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810