Protein Alignment Patsas and ZDHHC8

DIOPT Version :10

• Sequence 1: NP_001356957.1
• Gene: Patsas / 34634
• FlyBaseID: FBgn0029137
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001171953.1
• Gene: ZDHHC8 / 29801
• HGNCID: 18474
• Length: 778
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 56/262 - (21%)
• Similarity: 90/262 - (34%)
• Gaps: 94/262 - (35%)

  Fly   867 LATDELQQKLP-----IQPN-----------------ASIDFKLVIFGEADFLGALTAGPGQIGG 909
            |||.::..|.|     |:|.                 ||.:..:...|:       ..|.|: ||
Human    44 LATVDVDPKSPQYCQVIEPKDIHAKCELAFLHTSHCLASGEVMISSLGD-------VKGNGK-GG 100

  Fly   910 YPLANNPDGMNSAGPQSLTVSHGGGAGPLALPGGGGPFLSGGSGNPSIPSRISSPTNTHRRNELL 974
            :.|.:. :.....|    |....|||.||     |..|......|..|.:..::|       .:|
Human   101 FVLLDG-ETFEVKG----TWERPGGAAPL-----GYDFWYQPRHNVMISTEWAAP-------NVL 148

  Fly   975 TSSFR---------SSH------SGHSSLATLSVGISTGHVPRQLDAQLRFKYSGGEGLQEGFCR 1024
            ...|.         .||      ..|..:.|||  :..|.:|    .::||.::  ....:||.
Human   149 RDGFNPADVEAGLYGSHLYVWDWQRHEIVQTLS--LKDGLIP----LEIRFLHN--PDAAQGFV- 204

  Fly  1025 QCAISFNVE----------------LLPSAQITNWDVLSAEIPSQFYLVLDVVNLTAQEMSLNYT 1073
            .||:|..::                .:|..::..|  |..|:|.   |:.|:: |:..:..| |.
Human   205 GCALSSTIQRFYKNEGGTWSVEKVIQVPPKKVKGW--LLPEMPG---LITDIL-LSLDDRFL-YF 262

  Fly  1074 SN 1075
            ||
Human   263 SN 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	99..343	CDD:440430
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		DHHC	453..567	CDD:396215
ZDHHC8	NP_001171953.1	DHHC	99..224	CDD:396215	32/150 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	293..352
		PHA03247	<333..771	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	509..540