DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Patsas and Zdhhc1

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_008770707.1	Gene:	Zdhhc1 / 291967	RGDID:	1589775	Length:	502	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	72/287 - (25%)
Similarity:	105/287 - (36%)	Gaps:	100/287 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   336 LYGEVKKKSRWIPSVSESW--------GWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAIPITW 392
            |.|:..:::.|      ||        .||          |:|| |:|:.:|   .::..:|..|
  Rat    31 LQGQRSRRNGW------SWPPHPLQIVAWL----------LYLF-FAVIGFG---VLVPLLPHHW 75

  Fly   393 NILRRSHYCF---------IYWNAVMWISWAIANRRDPGYI-PLSSDAYYRAIKQIPYFDKLKKR 447
              :...:.|.         ::..||. |..|.||.||..|. ||            |.|::.:..
  Rat    76 --VPAGYACMGAIFAGHLVVHLTAVS-IDPADANVRDKSYSGPL------------PIFNRSQHA 125

  Fly   448 NVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFT 512
            :|:....|:.|......|:|||..||:||..|||||.::.||||.||...|...|.|..:.....
  Rat   126 HVIEDLHCNLCDVDVSARSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLL 190

  Fly   513 IYFACYCVMIEGF------------------------------------------TMLYVLGLIE 535
            :..|.| |.:|.|                                          .:|.:|||:.
  Rat   191 VLVATY-VFVEFFVNPMRLRTNQHFEVLKNHTDVWFVFLPAAPVETQAPAILALAALLILLGLLS 254

  Fly   536 AVVFCGLGWILTCTSILHACMNLTTNE 562
            ..:   ||.:| |..|......|||.|
  Rat   255 TAL---LGHLL-CFHIYLMWHKLTTYE 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185	72/287 (25%)
		DHHC	455..567	CDD:334580	42/150 (28%)
Zdhhc1	XP_008770707.1	DHHC	126..281	CDD:396215	43/157 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900