DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and Zdhhc8

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001365948.1	Gene:	Zdhhc8 / 27801	MGIID:	1338012	Length:	775	Species:	Mus musculus

Alignment Length:	287	Identity:	85/287 - (29%)
Similarity:	130/287 - (45%)	Gaps:	78/287 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 KKSRWIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIR----AIPITWNILRRSHYCF 402
            |.:::|| |:.:...|.|.:     .|| |:|:.      .::.|    |||:...||    :.|
Mouse    10 KPAKYIP-VATAAALLVGSS-----TLF-FVFTC------PWLTRAVSPAIPVYNGIL----FLF 57

  Fly   403 IYWNAVMWISWAIANRRDPGYIPLSSDAY-----YRAIKQIPYFDKLKKRNVML-TRLCHSCRCL 461
            :..|      :::|...|||..|.:.:..     :||    |.:..:..|.:.: .:.|.:|...
Mouse    58 VLAN------FSMATFMDPGVFPRADEDEDKEDDFRA----PLYKNVDVRGIQVRMKWCATCHFY 112

  Fly   462 RPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIEGFT 526
            ||.|..||.||:.||..||||||::.||:|.||..:||||:||:          :.:.|.:..|.
Mouse   113 RPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFLLSL----------SAHMVGVVAFG 167

  Fly   527 MLYVL----GL------IEAVVFC--GLGWI----LTCTSILHACMNLTTNEMFNYKRYPYLRDK 575
            :||||    ||      |...|.|  ||.:|    ||...::......||||...
Mouse   168 LLYVLNHSEGLGAAHTTITMAVMCVAGLFFIPVIGLTGFHVVLVTRGRTTNEQVT---------- 222

  Fly   576 RGRYQ---NPFSRGPILNLLEFFVCLP 599
             |:::   |||:||...| :|..:|.|
Mouse   223 -GKFRGGVNPFTRGCYGN-VEHVLCSP 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	48/127 (38%)
Zdhhc8	NP_001365948.1	DHHC	99..224	CDD:396215	48/145 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900