Protein Alignment Patsas and dhhc-13

DIOPT Version :10

• Sequence 1: NP_001356957.1
• Gene: Patsas / 34634
• FlyBaseID: FBgn0029137
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_500889.2
• Gene: dhhc-13 / 186797
• WormBaseID: WBGene00019257
• Length: 593
• Species: Caenorhabditis elegans
• Alignment Length: 572
• Identity: 142/572 - (24%)
• Similarity: 234/572 - (40%)
• Gaps: 129/572 - (22%)

  Fly   125 GEVSEVENLVDKFGMECLSARDRHGYTPAHWIALNGNVQLMRYLIERTAPIDLPCLGTQGPRPIH 189
            ||:..|..|::  |....:..|..|....||.|:|..:.:::.|:...|.|:| ..|.....|:|
 Worm    46 GEIQTVRFLLN--GHVSANEFDHEGCGLLHWAAINNKLDIIQLLLSHRADINL-IGGNMKSTPLH 107

  Fly   190 WACRKGHASVVQVLLQAGVAVNAADFKGLTPLHLACMYGRTATAAYLLGMGALNNLTDIN---GD 251
            |||.......|..|::.|......:..|.||||||...|.....||||  ...:|:.|..   |.
 Worm   108 WACYNSQFGAVMALVKNGADPTIKNINGETPLHLAACTGNFIIIAYLL--VKFDNIKDTRDNLGR 170

  Fly   252 TALHWAAYKGHADLMRLLMYSGVE--LQKTDN-FGSTPLHLACLSGNMT-CVRLLCEKSQLDLEP 312
            :||..||.|... |..:.:::.|:  |..||: .|:|.||:.....|:. .|.|:|  |..|...
 Worm   171 SALMMAADKSFG-LFPIRIFTKVDAYLDFTDDEKGNTALHILAARQNLKGVVELIC--SGADDTK 232

  Fly   313 RDKNG---------KTPIMLAQAHQHQDVVRLLYGEVKKK--SRWI------PSVSESWGWLFGG 360
            .|.||         |...::.:....:::..|  |.:.:|  |||.      .::|   |.:.|.
 Worm   233 TDNNGVSARDLMDNKFRNLVDKQVTARNICEL--GTICEKVTSRWFLGQFFTATIS---GVMIGA 292

  Fly   361 AGDSKGPLFLFLFSVLLWGY--------------PMYMIRAIPITW---------NILRRSHYCF 402
            |   .|..||..|.|:|.|.              .|.....:|:|:         .:|..:....
 Worm   293 A---TGLYFLTNFWVVLGGLALTALLLFILVQRRQMDQFGCLPVTYIFWMGIAEFALLIFNSNGL 354

  Fly   403 IYWNAVMWIS--WAIANR-------RDPGYIPLSSDAYYRAIKQIPYFDKLKKRNVMLTRLCHSC 458
            ::|:.::::.  |.|:..       .:||.:|.|:..:...||.:        ....:.|.|.:|
 Worm   355 VHWSVLIFVCSIWVISASFYWILILTNPGVLPRSTTPFKDFIKDL--------EEKQIDRYCFTC 411

  Fly   459 RCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIE 523
            ...:...:.||..|::||..||||||:|:.||..:|...|..|.|::.:   |.:::....:.:.
 Worm   412 WIPKTSSSHHCSQCDKCVDGFDHHCPWIHKCVYRKNLRAFVFFCLTIFM---FHVFYVLLLLYMI 473

  Fly   524 GFTM-------------LYVLGLIEAV--VFCGLGWILTCTSILHACMNLTTNEMFNYKR----- 568
            |.:|             |.|:.||.|:  || |.| .:|||.......:::|.|:...:|
 Worm   474 GASMNASGFEQTLNDHGLMVISLILAIPHVF-GAG-AITCTQFSQISRHVSTIEIIRKQRLQRNS 536

  Fly   569 ------------YPYLRDKRGRYQNPFSRGPILNLLEFFVCLPDR-GDDNDL 607
                        :.|.:..:.|.:|      :.|||.|     |: ||..::
 Worm   537 SEKTITSPEHNPWEYKQSVKTRIRN------VCNLLAF-----DKFGDGEEI 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	99..343	CDD:440430	65/233 (28%)
		ANK repeat	148..181	CDD:293786	9/32 (28%)
		ANK repeat	187..214	CDD:293786	8/26 (31%)
		ANK repeat	216..247	CDD:293786	13/30 (43%)
		ANK repeat	249..280	CDD:293786	9/35 (26%)
		ANK repeat	282..314	CDD:293786	10/32 (31%)
		DHHC	453..567	CDD:396215	38/128 (30%)
dhhc-13	NP_500889.2	ANKYR	<41..254	CDD:440430	63/215 (29%)
		ANK repeat	67..98	CDD:293786	9/31 (29%)
		ANK repeat	101..132	CDD:293786	8/30 (27%)
		ANK repeat	204..234	CDD:293786	10/31 (32%)
		DHHC	405..530	CDD:396215	38/129 (29%)