DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and dhhc-1

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_510510.1	Gene:	dhhc-1 / 181606	WormBaseID:	WBGene00008606	Length:	295	Species:	Caenorhabditis elegans

Alignment Length:	265	Identity:	70/265 - (26%)
Similarity:	99/265 - (37%)	Gaps:	86/265 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 FLFSVLL-WGYPMYMIRAIPITWN-------ILRRSHYCF------IYWNAVMWISW-------A 414
            |:|.:|| .|..::::..:| ||.       ::|.:  ||      :|.|.|..|..       |
Worm    32 FIFLILLPCGILLHLLYVLP-TWYPVMGEAWVIRAT--CFGVLVFNLYSNWVYMIKTGPNGHHSA 93

  Fly   415 IANRRDPGYIPLSSDAYYRAIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYF 479
            :.|...|||                             :.||||..:.||||.||.||:.|:...
Worm    94 LPNVIKPGY-----------------------------KHCHSCHSMSPLRAHHCPVCDVCILRR 129

  Fly   480 DHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIEGFTMLYVLGL--IEAVVFCGL 542
            ||||.|...|||..|:.:|...|:::.:   .|:....|...:....|...:|.  |..||...|
Worm   130 DHHCSFGAVCVGHFNQRYFVAAVINLFI---MTLPLVSYSWSLLNIKMTNEIGFGNIWQVVIPHL 191

  Fly   543 GWILTCTSI---LHACM------------NLTTNEMF----NYKRYPYLRDKRGRYQNPFSRGPI 588
            .||....||   ||..:            .|.|.::|    ...|..:|.|... ||
Worm   192 AWIAGYISIYQFLHVLLFVFTFTVSLFTFYLLTAQVFCIYQGQTRIEFLMDVHA-YQ-------- 247

  Fly   589 LNLLE 593
            |.|||
Worm   248 LGLLE 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	41/132 (31%)
dhhc-1	NP_510510.1	zf-DHHC	98..240	CDD:279823	45/173 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810