DRSC/TRiP Functional Genomics Resources

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Protein Alignment Patsas and ZDHHC19

DIOPT Version :9

Sequence 1:NP_001356957.1 Gene:Patsas / 34634 FlyBaseID:FBgn0029137 Length:613 Species:Drosophila melanogaster
Sequence 2:NP_001034706.1 Gene:ZDHHC19 / 131540 HGNCID:20713 Length:309 Species:Homo sapiens


Alignment Length:268 Identity:68/268 - (25%)
Similarity:108/268 - (40%) Gaps:35/268 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   342 KKSRWIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAIPITWNILRRSHYCFIYWN 406
            |:...:|.|...| :|         |.....|:|:|..:...:..|.|..| :.:...:.|....
Human    12 KEPHPLPLVPRPW-FL---------PSLFAAFNVVLLVFFSGLFFAFPCRW-LAQNGEWAFPVIT 65

  Fly   407 AVMWI----SWAIANRRDPGYIPLSSDAYYRAIKQIPYFDKLKKRNVMLTRL--CHSCRCLRPLR 465
            ..:::    |....|..|||.:      :..:.:|.|....:...|....||  |..|...||.|
Human    66 GSLFVLTFFSLVSLNFSDPGIL------HQGSAEQGPLTVHVVWVNHGAFRLQWCPKCCFHRPPR 124

  Fly   466 AKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFACYCVMIE----GFT 526
            ..||..||.||..|||||.::.||:|.||..:|.|.|||:.: .|..:...|...::.    .|:
Human   125 TYHCPWCNICVEDFDHHCKWVNNCIGHRNFRFFMLLVLSLCL-YSGAMLVTCLIFLVRTTHLPFS 188

  Fly   527 MLYVLGLIEAVVFCGLGWILTCTSILHACMNLTTNEMFNYKRYPYLRDKRGRYQNPFSRGPILNL 591
            ....:.::.||...||...|:...::.|....:.:..:..|    .|..:|  .|||.:|...|.
Human   189 TDKAIAIVVAVSAAGLLVPLSLLLLIQALSVSSADRTYKGK----CRHLQG--YNPFDQGCASNW 247

  Fly   592 LEFFVCLP 599
            . ..:|.|
Human   248 Y-LTICAP 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PatsasNP_001356957.1 ANKYR 113..306 CDD:223738
ANK repeat 148..181 CDD:293786
ANK repeat 187..214 CDD:293786
ANK repeat 216..247 CDD:293786
ANK repeat 249..280 CDD:293786
ANK repeat 282..314 CDD:293786
Ank_4 283..336 CDD:316185
DHHC 455..567 CDD:334580 35/115 (30%)
ZDHHC19NP_001034706.1 DHHC 109..>181 CDD:366691 30/72 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 280..309
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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