DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and slc66a1l

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001123690.1	Gene:	slc66a1l / 100170445	XenbaseID:	XB-GENE-5794175	Length:	303	Species:	Xenopus tropicalis

Alignment Length:	374	Identity:	75/374 - (20%)
Similarity:	121/374 - (32%)	Gaps:	144/374 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 GPR-PIH-------WACRKGHASVVQVLLQAG-------------VAVNAADFKGLTPLHLACMY 227
            ||| |:|       ..|.:|...:.|:|.|..             |::....|..|..|::|...
Frog     5 GPRHPLHALPLESGAVCLEGSPWIWQLLQQCVENAWEYWSVIVGLVSIACFLFAALPQLYVAHTN 69

  Fly   228 GRTATAAYLLGMGALNNLTDINGD------------------TALHWAAYKGHADLMRLLMYSGV 274
            ||...|   |.:|.|  |..:.||                  ||:.:.    :.|::.:..:|..
Frog    70 GRVDQA---LSLGFL--LCWLGGDFTNFIGCYLTNQLPLQIITAIFYV----NMDIIMISQFSYY 125

  Fly   275 ELQKTDNFGSTPLHLACLSGNMTCVRL-LCEKSQLDLEPRDKNGKTPIMLAQAHQHQDVVRLLYG 338
            :|:.....|:..|...|:|..:..:.| :...|||.|:..|||             .||
Frog   126 KLKNNRLKGNGSLKGICISWVLLAITLSILLPSQLLLKKYDKN-------------TDV------ 171

  Fly   339 EVKKKSRWIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWG--YP-MYMIRAIPITWNILRRSHY 400
            |:.:||..|..:|   |::.|           ::.||...|  :| :|.        |..|:|
Frog   172 EISQKSLGITEMS---GFICG-----------YVSSVFYLGSRFPQLYK--------NFHRKS-- 212

  Fly   401 CFIYWNAVMWISWAIANRRDPGYIPLSSDAYYRAIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLR 465
                .....::.:|:|                                 ||....:....|..|.
Frog   213 ----TEGTSYLLFALA---------------------------------MLGNCTYGTSLLLKLP 240

  Fly   466 AKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIY 514
            |    |.:....|..||.|::....|        :.:|...:...|.||
Frog   241 A----VGHHMSQYIMHHLPWLIGSFG--------VLILDFFMTAQFIIY 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738	34/161 (21%)
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786	8/46 (17%)
		ANK repeat	216..247	CDD:293786	10/30 (33%)
		ANK repeat	249..280	CDD:293786	7/48 (15%)
		ANK repeat	282..314	CDD:293786	9/32 (28%)
		Ank_4	283..336	CDD:316185	14/53 (26%)
		DHHC	455..567	CDD:334580	13/60 (22%)
slc66a1l	NP_001123690.1	PQ-loop	44..103	CDD:282099	14/63 (22%)
slc66a1l	NP_001123690.1	PQ-loop	185..238	CDD:282099	15/110 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910