DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Patsas and zdhhc23a

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_021327278.1	Gene:	zdhhc23a / 100150190	ZFINID:	ZDB-GENE-060526-38	Length:	434	Species:	Danio rerio

Alignment Length:	276	Identity:	66/276 - (23%)
Similarity:	106/276 - (38%)	Gaps:	69/276 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 LFLFLFSVLLWGYPMYMIRAIP---ITWNILRRSHYCFIYWNAVMWISW--AIANRRDPGYIP-- 425
            |.|.||| |.:.|.:::...:|   :|       |...:.....|.::.  .:..::.||::.
Zfish   130 LSLALFS-LAYMYYLFLTEIVPRGDVT-------HLQVVTATTGMMLTLISLVRTKQGPGFVKSQ 186

  Fly   426 -----------------LSSDAYYR-AIKQIPYFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVC 472
                             |:.|...| .:..:.....:||:       |..|:.:||.||.|||:|
Zfish   187 SLALGINSSLATNRSTNLTLDTDLRNGVSHLKGEKDVKKK-------CPVCQLVRPPRAGHCRIC 244

  Fly   473 NRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSF--TIYFACYCVMIEGFT-MLYVLGLI 534
            ..||...||||.:|.:|||..|...|.|.:|...:...:  ::.....|.....|| |||..|:.
Zfish   245 GACVLRMDHHCVWINSCVGQANHRQFILTLLLFLLTSFYGISLVLRSICPKQSLFTAMLYCPGVY 309

  Fly   535 E-------------AVVFCGLGWILTCTSILHACMNLTTNEMFNYKRYPYLRDKRGRYQ------ 580
            .             :|:..|....|....|::...|:|..|     ....||:|.||.:
Zfish   310 NQYSTALCFTCVWYSVIITGGLLHLFILQIINVSCNVTERE-----AQIALRNKTGRRRFCGLVV 369

  Fly   581 --NPFSRGPILNLLEF 594
              ...|||.:.|.::|
Zfish   370 ETGDHSRGFLQNWIQF 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	38/127 (30%)
zdhhc23a	XP_021327278.1	zf-DHHC	224..352	CDD:307600	40/139 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900