DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and zdhhc16

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_031760679.1	Gene:	zdhhc16 / 100145301	XenbaseID:	XB-GENE-957764	Length:	371	Species:	Xenopus tropicalis

Alignment Length:	320	Identity:	76/320 - (23%)
Similarity:	116/320 - (36%)	Gaps:	87/320 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   332 VVRLLYGEVKKKSRWIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYM-IRAIP------ 389
            :|.|.|.........|.|:.|...||........|.:|:.|..||.....:.: |..:|
Frog    40 IVSLAYNSFTNSDVVIESLFEPVYWLVDHVTRWFGIVFVALVIVLTSSIVLIVYICVLPLIIQTY 104

  Fly   390 ----ITWNILRRSHYCFIYWNAVMWISWAIANRRDPGYIPLSSDAYYRAIKQIPYFDKLKKRNVM 450
                |.|      |..:.:||.:|.:.                 .||:||...|.:....:.::.
Frog   105 STPWIYW------HVIYGHWNLIMIVF-----------------HYYKAITTPPGYPSQMETDIP 146

  Fly   451 LTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIY- 514
            ...:|..|...:|.|..||.:|:|||...|||||::.||||..|..:||.|.|.:.:.|   ||
Frog   147 SVSICRKCIAHKPARTHHCSICSRCVLKMDHHCPWLNNCVGHYNHRYFFSFCLFMTMGC---IYC 208

  Fly   515 -FACYCVMIEGFTMLYVLGLIE-----------------------------AVVFCGLGWILTCT 549
             |:...:..|.::.:..:.|.|                             .:::.   |:| |:
Frog   209 SFSSRVMFREAYSAIEKMKLQEKERLQFAANETYNDTPPPTFTFRERMFHKCIIYL---WVL-CS 269

  Fly   550 SIL---------HACMNLTTNEM-----FNYKRYPYLRDKRGRYQNPFSRGPILNLLEFF 595
            |:.         || |.:|..|.     .|.|....|......:.||:|.|...|...||
Frog   270 SVALALGALTLWHA-MLITRGETSIERHINKKERKRLESIGKVFYNPYSYGRSGNWKVFF 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185	1/3 (33%)
		DHHC	455..567	CDD:334580	41/156 (26%)
zdhhc16	XP_031760679.1	DHHC	150..299	CDD:396215	40/156 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910