DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Patsas and zdhhc20b

DIOPT Version :9

Sequence 1:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_005162815.2	Gene:	zdhhc20b / 100001188	ZFINID:	ZDB-GENE-091117-30	Length:	409	Species:	Danio rerio

Alignment Length:	313	Identity:	78/313 - (24%)
Similarity:	112/313 - (35%)	Gaps:	99/313 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   346 WIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAIPITWN-------ILRRSHYCFI 403
            |||                    .:|:..|:.|.|..|::....:|.:       .|...|..|:
Zfish    48 WIP--------------------VIFIALVVCWSYYAYVVELCLLTISSTGEKIVYLVVFHLSFV 92

  Fly   404 YWNAVMWISWAI-----ANRRDPGYIPLSSDAYYRAIKQIPYFDK--LKKRNVML---------- 451
            .:   :|..|..     ||......:|.|....|.. :|.|...:  |||....|
Zfish    93 MF---VWSYWKTIFTKPANPSKEFCLPKSEKEQYEK-EQRPETQQEILKKVATSLPLYTRTGAGA 153

  Fly   452 TRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLSVAVNCSFTIYFA 516
            .|.|..|:.::|.|..||..|:.||...|||||::.||||..|..:|.||:          .|..
Zfish   154 IRYCDRCQVIKPDRCHHCSACDMCVLKMDHHCPWVNNCVGFSNYKFFILFL----------TYSL 208

  Fly   517 CYCVMIEGFTMLYVL-----------------GLIEA-----VVFCGLGWILTCTSIL-----HA 554
            .||:.|....:.|.:                 .|.|:     |:|......:.|.|||     |.
Zfish   209 VYCLFIAASVLQYFIKFWTLCRRKSAENCPKSDLPESHAKFHVLFLFFVAAMFCISILSLFTYHL 273

  Fly   555 CM---NLTTNEMFNYKRYPYLRDKRGRYQNPFSRGPILNLLEFFVCLPDRGDD 604
            .:   |.:|.|.|   |.|..|:  |..:|.||.|...|:.:.|      ||:
Zfish   274 WLVGKNRSTIEAF---RAPVFRN--GPDKNGFSLGFSKNIAQVF------GDE 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	40/141 (28%)
zdhhc20b	XP_005162815.2	zf-DHHC	44..342	CDD:327686	78/313 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910