DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ced-12 and AT1G03620

DIOPT Version :9

Sequence 1:	NP_609548.1	Gene:	Ced-12 / 34633	FlyBaseID:	FBgn0032409	Length:	724	Species:	Drosophila melanogaster
Sequence 2:	NP_001321012.1	Gene:	AT1G03620 / 839448	AraportID:	AT1G03620	Length:	297	Species:	Arabidopsis thaliana

Alignment Length:	263	Identity:	52/263 - (19%)
Similarity:	103/263 - (39%)	Gaps:	59/263 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 LNALFVKADEGRRRTIAQTISAKQFRLALIGNGLGTEMTHQLYVLQTLTLGLLEKRMRMKMNAQD 308
            :..||.:::..:.:.:..|:|.                      ||...|..|:.||.:..:...
plant    72 IGGLFTRSNRRQDKAVDYTLSP----------------------LQEERLQRLQDRMVVPFDETR 114

  Fly   309 QDAHEKIKELRRIAFDDNTNALNQNDDHIRRGGGSGAGNVNF----SQYYKKLGFKCDINPAQDF 369
            .|..|.:|.|..:||.                      ||:.    ::.:|::|:: ..||:.||
plant   115 PDHQESLKALWNVAFP----------------------NVHLTGLVTEQWKEMGWQ-GPNPSTDF 156

  Fly   370 IETPPGILALDCMVYFARNYTQQYAKIVRENSCRADEHECPFGRTSIELVKVLCDILRIGEPPAE 434
              ...|.:||:.:::.||.|...:.:::.:......:.|.||....|.:..:|..:|.:...|..
plant   157 --RGCGFIALENLLFSARTYPVCFRRLLLKQRGDRAKWEYPFAVAGINISFMLIQMLDLQNNPKP 219

  Fly   435 Q---SGDFQPMFFTHDSPFEEFFCICVITLNRTWKDMRATAEDFSTTFSVVREQIQRTLKGRPEN 496
            :   ..:|..:....:..|:..:||....::..|..|.|:..:|:......|.|::|.|     :
plant   220 KCLPGMNFLKLLEEDERAFDVLYCIAFAMMDAQWLAMHASYMEFNEVLQATRNQLEREL-----S 279

  Fly   497 LDD 499
            |||
plant   280 LDD 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ced-12	NP_609548.1	DUF3361	122..275	CDD:288674	4/30 (13%)
		ELMO_CED12	296..474	CDD:282570	37/184 (20%)
		PH_ELMO1_CED-12	546..673	CDD:270166
AT1G03620	NP_001321012.1	ELMO_CED12	100..267	CDD:398415	38/191 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102058
Panther	1	1.100	-	-	LDO	PTHR12771
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910